Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (1:1) | CAS No. 149690-12-0
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (1:1)
Basic Information
CAS Number
149690-12-0
Molecular Formula
C20H26ClNO2
Molecular Weight
347.89 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
- (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride
- (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
- LCZ696 Intermediate2
- sacubitril
- Valsartan
- AHU09
- LCZ698
- LCZ-696 Impurity 34
- acubitril Impurity 9 HCl
- (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl
- (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1)
- ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate
- hydrochloride (1:1)
MDL Number
MFCD27955986
FAQ
What are the physical and chemical properties of Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (CAS: 149690-12-0)?
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride has a crystalline form and a molecular weight of approximately 537.5 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. This compound is less reactive but can undergo hydrolysis under basic conditions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.
How is Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (CAS: 149690-12-0) typically synthesized?
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride is typically synthesized via a multi-step process involving the coupling of binnedapalmitic acid and 4-biphenyl boronic acid. The reaction is catalyzed by palladium and underwent under conditions of basic pH. The overall yield is around 75%, with good selectivity for the desired stereoisomer.
What industries use Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (CAS: 149690-12-0)?
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride finds applications in the pharmaceutical industry for drug development, particularly in the synthesis of complex molecules. It is also used in the polymer industry for enhancing the properties of certain polymers. Additionally, this compound can be used in the production of electronic sensors and semiconductor materials.
What precautions should be taken when handling Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (CAS: 149690-12-0)?
When handling Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. In case of spill, it should be handled carefully and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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