Compound Q&A
How is Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (CAS: 149690-12-0) typically synthesized?
Answer
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride is typically synthesized via a multi-step process involving the coupling of binnedapalmitic acid and 4-biphenyl boronic acid. The reaction is catalyzed by palladium and underwent under conditions of basic pH. The overall yield is around 75%, with good selectivity for the desired stereoisomer.
About
CAS No
149690-12-0
English Name
Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (1:1)
Molecular Formula
C20H26ClNO2
Molecular Weight
347.89 g/mol
SMILES
Cl.CCOC(=O)[C@H](C)C[C@H](N)Cc1ccc(cc1)c2ccccc2
InChIKey
MYJTZLYRAWUSLB-WSCVZUBPSA-N
Last Updated: 2025-09-23 10:23
