Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride (1:1)(CAS: 149690-12-0)

Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride has a crystalline form and a molecular weight of approximately 537.5 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. This compound is less reactive but can undergo hydrolysis under basic conditions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride is typically synthesized via a multi-step process involving the coupling of binnedapalmitic acid and 4-biphenyl boronic acid. The reaction is catalyzed by palladium and underwent under conditions of basic pH. The overall yield is around 75%, with good selectivity for the desired stereoisomer.

Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride finds applications in the pharmaceutical industry for drug development, particularly in the synthesis of complex molecules. It is also used in the polymer industry for enhancing the properties of certain polymers. Additionally, this compound can be used in the production of electronic sensors and semiconductor materials.

When handling Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. In case of spill, it should be handled carefully and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.