(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol

Basic Information

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CAS Number

149082-03-1

Molecular Formula

C8H10N2O3

Molecular Weight

182.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

66.0 to 70.0 deg-C

Boiling Point

349℃ at 760 mmHg

Density

1.293

Flash Point

165.3°C

Refractive Index

1.581

SMILES

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CC1=CN=C(C(=C1[N+](=O)[O-])C)CO

InChI

InChI=1S/C8H10N2O3/c1-5-3-9-7(4-11)6(2)8(5)10(12)13/h3,11H,4H2,1-2H3

InChIKey

KBCDOXSSYLFMHH-UHFFFAOYSA-N

LogP

1.62210

Complexity

192

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AC-8344
2-hydroxymethyl-3,5dimethyl-4-nitropyridine
EN300-175309
SCHEMBL3089370
(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol
(3,5-Dimethyl-4-nitro-2-pyridyl)-1-methanol
2-Pyridinemethanol, 3,5-dimethyl-4-nitro-
MFCD03426035
DTXSID20398774
AM84451
3,5-DIMETHYL-4-NITRO-2-HYDROXYMETHYL PYRIDINE
J-008549
KBCDOXSSYLFMHH-UHFFFAOYSA-N
D4026
3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine
AB14752
CS-W010746
(3,5-Dimethyl-4-nitro-pyridin-2-yl)-methanol;2-(Hydroxymethyl)-3,5-dimethyl-4-nitropyridine
AKOS015891698
A3269
DS-14790
SY038239
2-(Hydroxymethyl)-3,5-dimethyl-4-nitropyridine
(3,5-Dimethyl-4-nitro-2-pyridyl)-1-methanol, 97%
149082-03-1
3,5-Dimethyl-4-nitropyridine-2-methanol
NS00122760
3,5-Dimethyl-4-nitro-2-pyridinemethanol
CHEMBL4444883
2-hydroxymethyl-3,5-dimethyl-4-nitropyridine
FT-0614682

MDL Number

MFCD03426035

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1)?

(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1) is a crystalline solid with a molecular weight of approximately 228.14 g/mol. It is moderately soluble in water and organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can act as an electrophile in various organic reactions. It is stable under normal storage conditions but should be kept away from strong reducing agents and bases.

How is (3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1) typically synthesized?

(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1) can be synthesized through a multi-step process starting with 3,5-dimethyl-4-nitropyridine. The nitro group is reduced to an amino group using a suitable reducing agent, followed by alkylation with methanol. Common catalysts include sodium methoxide, and the reaction typically yields 80-90% purity under controlled conditions.

What industries use (3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1)?

(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those containing pyridine derivatives. It is also utilized in the polymer industry for modifying properties of polymers, and in the chemical sensors sector for developing gas sensing devices. Its reactivity makes it a valuable intermediate in semiconductor production as well.

What precautions should be taken when handling (3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1)?

When handling (3,5-Dimethyl-4-nitro-2-pyridinyl)methanol (CAS: 149082-03-1), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be done in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the SDS (Safety Data Sheet) for detailed emergency procedures and storage conditions.