(9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol

Basic Information

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CAS Number

125-73-5

Molecular Formula

C17H23NO

Molecular Weight

257.38 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

≥195 °C

Boiling Point

400.62°C (rough estimate)

Solubility

saline: soluble(lit.)

Refractive Index

1.5200 (estimate)

Specific Rotation

D20 +56.3° (c = 3 in abs alcohol)

SMILES

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CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4c3cc(cc4)O

InChI

InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1

InChIKey

JAQUASYNZVUNQP-PVAVHDDUSA-N

LogP

3.0804000000000022

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

491

Synonyms & References

English

Morphinan-3-ol,17-methyl-, (9a,13a,14a)-
Dextrorphan
DEXTRORPHAN D-TARTRATE
DEXTRORPHAN-D -TARTRATE
(+)-3-hydroxy-N-methylmorphinan
(+)-N-Methylmorphinan-3-ol
D-3-hydroxy-N-methylmorphinan
Dextro-Dromoran
Dextrorphane
d-Form of levorphanol
d-Levorphanol
O-Demethyl dextromethorphan
Racemorphan
Ro 1-6794
17-Methylmorphinan-3-ol
DextroMethorphan IMpurity B
(4bS,8aS,9S)-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthren-3-ol

FAQ

What are the physical and chemical properties of (9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol (CAS: 125-73-5)?

(9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol is a crystalline compound with a molecular weight of approximately 283.41 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol. This compound exhibits moderate reactivity, particularly in acidic environments. It is stable under normal conditions but can degrade upon prolonged exposure to light.

How is (9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol (CAS: 125-73-5) typically synthesized?

(9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol is often synthesized via a multi-step process starting from morphine or its precursors. The key steps involve ring closure and methylation reactions. This compound can be synthesized using various catalysts and reagents to achieve high selectivity and yield, making it suitable for pharmaceutical applications.

What industries use (9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol (CAS: 125-73-5)?

(9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol is primarily used in the pharmaceutical industry for the development of analgesic medications. It can also find applications in the research and development of new drugs for pain management and addiction treatment. This compound is also utilized in some specialized medical and chemical industries due to its unique properties.

What precautions should be taken when handling (9alpha,13alpha,14alpha)-17-Methylmorphinan-3-5 (CAS: 125-73-5)?

When handling (9alpha,13alpha,14alpha)-17-Methylmorphinan-3-ol (CAS: 125-73-5), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate disposal methods, and safety data sheets (SDS) should be consulted for detailed handling and disposal instructions.