Cefepime DiHCl | CAS No. 107648-80-6

Cefepime DiHCl

Basic Information

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CAS Number

107648-80-6

Molecular Formula

C19H26Cl2N6O5S2

Molecular Weight

553.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O.Cl.[Cl-]

InChI

InChI=1S/C19H24N6O5S2.2ClH/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H/b23-12-;;/t13-,17-;;/m1../s1

InChIKey

XQQAUWFZBOTKFQ-MHRNPJSASA-N

LogP

1.19290

Complexity

874

Synonyms & References

English

Cefepime (hydrochloride)
CS-0031212
Maxipime
Cefepime hydrochloride anhydrous
2A1O4F5N0C
Cefepime HCl
AKOS030623159
BMY-28142 dihydrochloride
HY-108877
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;chloride;hydrochloride
Cepimax
Cepimex
107648-80-6
Maxcef
UNII-2A1O4F5N0C
Axepim
cefepime dihydrochloride
Cefepime hydrochloride
Pyrrolidinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methyl-, chloride, monohydrochloride, (6R-(6alpha,7beta(Z)))-
Cefepim dihydrochloride
Pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate
Pyrrolidinium, 1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate, [6R-[6α,7β(Z)]]-
(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-[1-(1-methylpyrrolidinyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid hydrochloride monohydrate
CEFEPIME HYDROCHLORIDE (BUFFERED WITH ARGININE)
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl- pyrrolidinium Inner Salt Hydrochloride Monohydrate
Cefepime dihydrochloride
Cefeprime dihydrochloride
1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium chloride hydrochloride
CEFEPIME HCL
CefepiMe hydrochloric
l-[[(6R,7R)-7-[2-(2-amino-4-thiazolyl)-glyoxylamido]-2-carboxy-8-oxo-5-thia-l-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidi

MDL Number

MFCD01687679

Customs Code

2941905990

FAQ

What are the physical and chemical properties of Cefepime DiHCl (CAS: 107648-80-6)?

Cefepime DiHCl is a crystalline compound with a molecular weight of approximately 613.46 g/mol. It has a high solubility in water and poor solubility in organic solvents. The compound shows moderate reactivity towards basic conditions and is stable under acidic conditions. It is commonly used as an antibacterial agent and has a pH range of 2-5.

How is Cefepime DiHCl (CAS: 107648-80-6) typically synthesized?

Cefepime DiHCl is synthesized through a multi-step process involving acylation, reduction, and amidation. The key steps involve the introduction of a dihydrochloride group to the cefepime structure. Commonly used catalysts include palladium complexes, and the overall yield is around 60-70%. The process requires careful control of temperature and pH to achieve high selectivity and purity.

What industries use Cefepime DiHCl (CAS: 107648-80-6)?

Cefepime DiHCl is primarily used in the pharmaceutical industry as an antibacterial agent. It is widely applied in the production of antibiotics to treat various bacterial infections. Its use in the pharmaceutical sector is significant, and it is also sometimes used in veterinary medicine for similar purposes.

What precautions should be taken when handling Cefepime DiHCl (CAS: 107648-80-6)?

When handling Cefepime DiHCl, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of spills, use appropriate spill kits, and immediately consult the Safety Data Sheet (SDS) for further guidance. It is advisable to use a fume hood during preparation to minimize inhalation risks.