Cefepime DiHCl(CAS: 107648-80-6)

Cefepime DiHCl is a crystalline compound with a molecular weight of approximately 613.46 g/mol. It has a high solubility in water and poor solubility in organic solvents. The compound shows moderate reactivity towards basic conditions and is stable under acidic conditions. It is commonly used as an antibacterial agent and has a pH range of 2-5.

Cefepime DiHCl is synthesized through a multi-step process involving acylation, reduction, and amidation. The key steps involve the introduction of a dihydrochloride group to the cefepime structure. Commonly used catalysts include palladium complexes, and the overall yield is around 60-70%. The process requires careful control of temperature and pH to achieve high selectivity and purity.

Cefepime DiHCl is primarily used in the pharmaceutical industry as an antibacterial agent. It is widely applied in the production of antibiotics to treat various bacterial infections. Its use in the pharmaceutical sector is significant, and it is also sometimes used in veterinary medicine for similar purposes.

When handling Cefepime DiHCl, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of spills, use appropriate spill kits, and immediately consult the Safety Data Sheet (SDS) for further guidance. It is advisable to use a fume hood during preparation to minimize inhalation risks.