Compound Q&A

How is Cefepime DiHCl (CAS: 107648-80-6) typically synthesized?

Answer

Cefepime DiHCl
Cefepime DiHCl is synthesized through a multi-step process involving acylation, reduction, and amidation. The key steps involve the introduction of a dihydrochloride group to the cefepime structure. Commonly used catalysts include palladium complexes, and the overall yield is around 60-70%. The process requires careful control of temperature and pH to achieve high selectivity and purity.

About

English Name Cefepime DiHCl
Molecular Formula C19H26Cl2N6O5S2
Molecular Weight 553.5 g/mol
SMILES C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O.Cl.[Cl-]
InChIKey XQQAUWFZBOTKFQ-MHRNPJSASA-N
Last Updated: 2025-10-16 16:48

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