3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine(CAS: 1496551-71-3)

The compound 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is a crystalline solid with a molecular weight of approximately 500.52 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and acetonitrile. The compound is known for its high reactivity towards nucleophilic substitution, particularly due to the presence of the chloromethyl group.

3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is typically synthesized through a multi-step process, starting with the benzoylation of uridine followed by the introduction of a chloromethyl group. The synthesis involves the use of acylating agents and chlorinating reagents, and the overall process yields the desired product with good selectivity and moderate to high yield.

3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is primarily used in the pharmaceutical industry for its potential as an antiviral agent. It is also of interest in research applications for its structural and reactive properties, making it relevant to fields such as polymer chemistry and sensor technology.

When handling 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or in a fume hood due to its potential volatility and reactivity. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly cleaned. Safety data sheets (SDS) should be consulted for detailed emergency procedures and storage guidelines.