3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine

Basic Information

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CAS Number

1496551-71-3

Molecular Formula

C24H21ClN2O7

Molecular Weight

484.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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C[C@]1([C@@H]([C@H](O[C@H]1n2ccc(=O)[nH]c2=O)COC(=O)c3ccccc3)OC(=O)c4ccccc4)Cl

InChI

InChI=1S/C24H21ClN2O7/c1-24(25)19(34-21(30)16-10-6-3-7-11-16)17(14-32-20(29)15-8-4-2-5-9-15)33-22(24)27-13-12-18(28)26-23(27)31/h2-13,17,19,22H,14H2,1H3,(H,26,28,31)/t17-,19-,22-,24-/m1/s1

InChIKey

QUSIDKWVBPQGDG-PDKZGUECSA-N

LogP

2.5141

Topological Polar Surface Area

116.69000000000003 Å²

Hydrogen Bond Donor/Acceptor

1 / 9

Synonyms & References

English

((2R,3r,4r,5r)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-4-methyltetrahydrofuran-2-yl)methyl benzoate

FAQ

What are the physical and chemical properties of 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine (CAS: 1496551-71-3)?

The compound 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is a crystalline solid with a molecular weight of approximately 500.52 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and acetonitrile. The compound is known for its high reactivity towards nucleophilic substitution, particularly due to the presence of the chloromethyl group.

How is 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine (CAS: 1496551-71-3) typically synthesized?

3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is typically synthesized through a multi-step process, starting with the benzoylation of uridine followed by the introduction of a chloromethyl group. The synthesis involves the use of acylating agents and chlorinating reagents, and the overall process yields the desired product with good selectivity and moderate to high yield.

What industries use 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine (CAS: 1496551-71-3)?

3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine is primarily used in the pharmaceutical industry for its potential as an antiviral agent. It is also of interest in research applications for its structural and reactive properties, making it relevant to fields such as polymer chemistry and sensor technology.

What precautions should be taken when handling 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine (CAS: 1496551-71-3)?

When handling 3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-2'-methyluridine, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or in a fume hood due to its potential volatility and reactivity. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly cleaned. Safety data sheets (SDS) should be consulted for detailed emergency procedures and storage guidelines.