15(R)-15-METHYL PROSTAGLANDIN F2ALPHA

Basic Information

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CAS Number

35864-81-4

Molecular Formula

C21H36O5

Molecular Weight

368.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

SMILES

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CCCCCC(C)(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O

InChI

InChI=1S/C21H36O5/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)/b7-5-,14-12+/t16-,17-,18+,19-,21-/m1/s1

InChIKey

DLJKPYFALUEJCK-KKIXJVLHSA-N

LogP

3.433000000000003

Topological Polar Surface Area

97.99000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

473

Synonyms & References

English

(5Z,9alpha,11alpha,13E,15R)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid
15-methyl-15R-PGF2alpha
35864-81-4
PD021297
15(R)-METHYLPROSTAGLANDIN F2.ALPHA.
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9alpha,11alpha,13E,15R)-
SCHEMBL13508533
9.alpha.,11.alpha.,15R-Trihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid
15(S)-15-methyl Prostaglandin F2 alpha
15-EPICARBOPROST [USP IMPURITY]
15(R)-Methylprostaglandin F2
15(R)-15-Methylprostaglandin F2.alpha.
PROSTA-5,13-DIEN-1-OIC ACID, 9,11,15-TRIHYDROXY-15-METHYL-, (5Z,9.ALPHA.,11.ALPHA.,13E,15R)-
CARBOPROST TROMETAMOL IMPURITY B [EP IMPURITY]
15-Epicarboprost [USP]
A
DLJKPYFALUEJCK-KKIXJVLHSA-N
15(R)-Carboprost
KJ0LQC3LV9
ONO 373
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3R)-3-hydroxy-3-methyloct-1-enyl)cyclopentyl)-5-heptenoic acid
LMFA03010121
UNII-KJ0LQC3LV9
15(R)-15-Methyl prostaglandin F2alpha
(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid
(5Z,9.ALPHA.,11.ALPHA.,13E,15R)-9,11,15-TRIHYDROXY-15-METHYLPROSTA-5,13-DIEN-1-OIC ACID
15-methyl-15R-Prostaglandin F2alpha
9S,11R,15R-trihydroxy-15-methyl-5Z,13E-prostadienoic acid
15-Epicarboprost
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid
CHEBI:186036

MDL Number

MFCD00135246

FAQ

What are the physical and chemical properties of 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4)?

15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4) is a crystalline compound with a molecular weight of approximately 530.72 g/mol. It has a high solubility in organic solvents like ethanol and poor solubility in water. This compound is relatively stable under normal conditions but can undergo hydrolysis under acidic or basic conditions. It is a potent pro-inflammatory mediator and is used in various biological assays and research applications.

How is 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4) typically synthesized?

15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4) can be synthesized through a series of chemical reactions, including the synthesis of prostaglandin precursors, followed by selective methylation at the 15 position. Common catalysts include sodium hydride and other organometallic reagents. The yield and selectivity of the reaction can be optimized by controlling reaction conditions such as temperature and solvent choice.

What industries use 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4)?

15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4) is primarily used in the pharmaceutical industry for research into inflammation and pain management. It is also utilized in the development of new drugs and in biological assays. Some applications include the study of prostaglandin receptor mechanisms and the development of anti-inflammatory and analgesic agents.

What precautions should be taken when handling 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4)?

When handling 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA (CAS: 35864-81-4), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions. This compound is not known to be toxic but can cause skin and eye irritation if not handled properly.