Novel chiral gallium Lewis acid catalysts with semi-crown ligands for aqueous asymmetric Mukaiyama aldol reactions

Literature Information

Publication Date 2002-11-11
DOI 10.1039/B208411B
Impact Factor 6.222
Authors

Hui-Jing Li, Hong-Yu Tian, Yong-Jun Chen, Dong Wang, Chao-Jun Li


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Abstract

Asymmetric Mukaiyama aldol reactions in aqueous media (water–ethanol = 9:1) were catalyzed by chiral gallium catalysts with semi-crown ligands to give aldol products with good yields, syn-diastereoselectivities and enantioselectivities.

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