Novel chiral gallium Lewis acid catalysts with semi-crown ligands for aqueous asymmetric Mukaiyama aldol reactions
Literature Information
Hui-Jing Li, Hong-Yu Tian, Yong-Jun Chen, Dong Wang, Chao-Jun Li
Asymmetric Mukaiyama aldol reactions in aqueous media (water–ethanol = 9:1) were catalyzed by chiral gallium catalysts with semi-crown ligands to give aldol products with good yields, syn-diastereoselectivities and enantioselectivities.
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