Compound Q&A

How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?

Answer

(S)-Alpha-allyl-proline hydrochloride
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reaction between allyl bromide and proline. The reaction is catalyzed by a Lewis acid such as aluminum trichloride, and the product is obtained with good yield and high selectivity. The reaction typically proceeds in an organic solvent such as dichloromethane.

About

English Name (S)-Alpha-allyl-proline hydrochloride
Molecular Formula C8H14ClNO2
Molecular Weight 191.65800000000002 g/mol
SMILES C=CC[C@@]1(CCCN1)C(=O)O.Cl
InChIKey DIYYEOOBZVTROL-DDWIOCJRSA-N
Last Updated: 2025-10-31 17:33

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