2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid | CAS No. 99066-77-0
2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid
Basic Information
CAS Number
99066-77-0
Molecular Formula
C9H6N2O3
Molecular Weight
190.16 g/mol
AD
Basic Physical Properties
Boiling Point
561.5°C at 760 mmHg
Density
1.56
Flash Point
293.4°C
Refractive Index
1.71
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- AKOS001770443
- carboxyquinazolinone
- 99066-77-0
- MFCD00578120
- TJY
- 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid
- 2-QUINAZOLONE-4-CARBOXYLIC ACID
- AB06490
- 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid #
- SCHEMBL14072437
- AKOS006228481
- Quinazoline-4-carboxylic acid, 1,2-dihydro-2-oxo-
- 2-OXO-1,2-DIHYDRO-QUINAZOLINE-4-CARBOXYLIC ACID
- 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid
- EN300-120846
- DTXSID20337340
- JMRRYHBZGAQICA-UHFFFAOYSA-N
- 2-oxo-1,2-dihydroquinazoline-4-carboxylicacid
- SCHEMBL3558607
- AC-26857
- 2-oxo-1H-quinazoline-4-carboxylic acid
- FT-0682251
- 2-Oxo-1,2-dihydroquinazoline-4-carboxylic acid
- 4-Quinazolinecarboxylic acid, 1,2-dihydro-2-oxo-
- 2-Hydroxy-chinazolin-4-carbonsaeure
- 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid(SALTDATA: H2O)
- 2-oxohydroquinazoline-4-carboxylic acid
- 2-oxoquinazoline-4-carboxylic acid
- 4-Quinazolinecarboxylic acid,1,2-dihydro-2-oxo
MDL Number
MFCD00578120
Customs Code
2927000090
FAQ
What are the physical and chemical properties of 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid (CAS: 99066-77-0)?
2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid has a crystalline form with a molecular weight of approximately 216.21 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is moderately reactive and susceptible to hydrolysis under acidic conditions. It has a pKa of about 4.5, indicating its acidic nature.
How is 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid (CAS: 99066-77-0) typically synthesized?
2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid is typically synthesized through the condensation of 4-aminobenzoyl chloride with 1,3-dicarbonyl compounds such as trimesic acid. The reaction involves the use of a catalyst like tin(II) chloride to enhance the yield. The process is selective and yields up to 85% of 2-oxo-1,2-dihydro-4-quinazolinecarboxylic acid.
What industries use 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid (CAS: 99066-77-0)?
2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of materials. Additionally, it has applications in the development of sensors and semiconductors due to its unique chemical properties.
What precautions should be taken when handling 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid (CAS: 99066-77-0)?
When handling 2-Oxo-1,2-dihydro-4-quinazolinecarboxylic acid, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up with appropriate absorbents, and the material safety data sheet (MSDS) should be readily available for reference.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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