2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride | CAS No. 90942-38-4

2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride

Basic Information

CAS Number

90942-38-4

Molecular Formula

C9H11Cl2N

Molecular Weight

204.1 g/mol

AD

Basic Physical Properties

C1C(C1N)C2=CC(=CC=C2)Cl.Cl

InChI

InChI=1S/C9H10ClN.ClH/c10-7-3-1-2-6(4-7)8-5-9(8)11;/h1-4,8-9H,5,11H2;1H

InChIKey

QRDJNIKTHWYMIN-UHFFFAOYSA-N

LogP

2.576400000000001

Topological Polar Surface Area

26.02 Ų

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

149

Synonyms & References

English

  • 2-(3-Chlorophenyl)cyclopropanamine hydrochloride
  • Cyclopropylamine, 2-(m-chlorophenyl)-, hydrochloride (7CI)
  • 2-(3-Chlorophenyl)cyclopropylamine Hydrochloride
  • AKOS025287440
  • 2-(3-Chlorophenyl) cyclopropanamine HCl
  • 2-(3-Chlorophenyl)cyclopropylamine HCl
  • 90942-38-4
  • CS-0209475
  • EN300-83856
  • DA-40643
  • 2-(3-Chlorophenyl)cyclopropanaminehydrochloride
  • Y10415
  • 2-(3-chlorophenyl)cyclopropan-1-amine hydrochloride
  • SB78345
  • 2-(3-chlorophenyl)cyclopropan-1-amine;hydrochloride
  • MFCD19982549

MDL Number

MFCD19982549

FAQ

What are the physical and chemical properties of 2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4)?

2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4) is a white crystalline solid with a molecular weight of approximately 222.03 g/mol. It has a low melting point and excellent solubility in water and organic solvents. This compound is known for its basic properties and can react with acids to form the free amine. It is stable under normal conditions but should be stored away from strong acids and bases.

How is 2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4) typically synthesized?

2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4) is typically synthesized through a multi-step process involving the protection of a phenolic hydroxyl group, followed by the introduction of a cyclopropanation step, and then the formation of the amine and hydrochloride salt. Common solvents for these reactions include dichloromethane and acetonitrile, and the yield can range from 60% to 80%.

What industries use 2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4)?

2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the formulation of some pesticides and herbicides. Additionally, it can be used in research for the development of new materials and sensors.

What precautions should be taken when handling 2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4)?

When handling 2-(3-Chlorophenyl)cyclopropan-1-amine hydrochloride (CAS: 90942-38-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated fume hood to avoid inhalation of dust or fumes. In case of a spill, quickly contain it and clean up using appropriate methods. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.

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