2-Hydrazinobenzenesulfonamide

Basic Information

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CAS Number

90824-33-2

Molecular Formula

C6H9N3O2S

Molecular Weight

187.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CC=C(C(=C1)NN)S(=O)(=O)N

InChI

InChI=1S/C6H9N3O2S/c7-9-5-3-1-2-4-6(5)12(8,10)11/h1-4,9H,7H2,(H2,8,10,11)

InChIKey

CTEZEDIMFASQNI-UHFFFAOYSA-N

LogP

-0.3803999999999998

Topological Polar Surface Area

98.21 Å²

Hydrogen Bond Donor/Acceptor

5 / 5

Complexity

234

Synonyms & References

English

FT-0770251
CHEMBL176495
SCHEMBL1425352
90824-33-2
AKOS009496587
aromatic/heteroaromatic sulfonamide 24
PD180483
hydrazide deriv. 18
SB39796
2-Hydrazinobenzenesulfonamide
BDBM10879
2-hydrazinylbenzenesulfonamide
EN300-185937
2-Hydrazino-benzenesulfonamide
DTXSID00458683
2-hydrazinylbenzene-1-sulfonamide
2-Hydrazinylbenzenesulfonamide
Benzenesulfonamide,2-hydrazinyl-

MDL Number

MFCD03093797

FAQ

What are the physical and chemical properties of 2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2)?

2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2) is a crystalline compound with a molecular weight of approximately 220.18 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound is known for its reactivity towards nucleophiles and its ability to undergo substitution reactions. It has a melting point of around 140°C and is stable under normal conditions but should be handled in a fume hood to avoid inhalation exposure.

How is 2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2) typically synthesized?

2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2) can be synthesized through a multi-step process involving the sulfonation of benzenesulfonamide followed by the hydrazination reaction. This typically requires the use of hydrazine and a catalyst such as palladium on carbon. The reaction is carried out in a solvent like methanol or ethanol, and the yield can be up to 90% when optimized. This synthesis is performed under mild conditions to ensure high selectivity and purity.

What industries use 2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2)?

2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2) finds applications in various industries. It is used in the pharmaceutical sector for the synthesis of certain drugs due to its hydrazine group, which can participate in medicinal chemistry. In the polymer industry, it acts as a sulfonamide additive for improving the properties of polymers. Additionally, it is utilized in sensors and semiconductors for its electrochemical and electronic properties.

What precautions should be taken when handling 2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2)?

When handling 2-Hydrazinobenzenesulfonamide (CAS: 90824-33-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, immediately clean up with appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal and emergency response.