Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate | CAS No. 90407-15-1
Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate
Basic Information
CAS Number
90407-15-1
Molecular Formula
C11H9ClO2S
Molecular Weight
240.71 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate
- 7-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
- Benzo[b]thiophene-2-carboxylicacid, 7-chloro-, ethyl ester
- Ethyl 7-chloro-1-benzothiophene-2-carboxylate
- Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (ACI)
- Ethyl7-chlorobenzo[b]thiophene-2-carboxylate
- AA-516/33240003
- 7-Chloro-benzo[b]thiophene-2-carboxylic acid
- MFCD00834770
- DB-325892
- Benzo[b]thiophene-2-carboxylic acid, 7-chloro-, ethyl ester
- AKOS022172767
- 90407-15-1
- DTXSID50356347
- AS-8590
- SCHEMBL18264007
- ethyl 7-chloro-1-benzothiophene-2-carboxylate
MDL Number
MFCD00834770
FAQ
What are the physical and chemical properties of Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1)?
Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1) is a crystalline compound with a molecular weight of approximately 242.02 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and acetonitrile. The compound shows moderate reactivity with basic compounds and is susceptible to hydrolysis under certain conditions. It is often used in pharmaceutical and chemical synthesis due to its unique chemical structure.
How is Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1) typically synthesized?
Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1) is typically synthesized via a multi-step process involving acylation of 7-chlorobenzo[b]thiophene-2-carboxylic acid with ethyl chloroformate. This reaction is often catalyzed by an acid, such as sulfuric acid, and proceeds with good yield. The final product is obtained through recrystallization from an appropriate solvent.
What industries use Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1)?
Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1) finds applications in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drug candidates, particularly those targeting specific enzymes or receptors. Additionally, it is utilized in the development of sensors and materials due to its unique chemical properties.
What precautions should be taken when handling Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1)?
When handling Ethyl 7-chlorobenzo[b]thiophene-2-carboxylate (CAS: 90407-15-1), it is crucial to follow proper safety protocols. Always wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. Refer to the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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Supplier Information
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