![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid | CAS No. 896046-85-8
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid
Basic Information
CAS Number
896046-85-8
Molecular Formula
C13H16FNO2
Molecular Weight
237.27 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
1.234
Synonyms & References
English
- 1-(3-fluorobenzyl)piperidine-3-carboxylicacid
- 1-(3-Fluoro-benzyl)-piperidine-3-carboxylic acid
- FT-0766758
- 1-[(3-fluorophenyl)methyl]piperidine-3-carboxylic Acid
- AKOS000125278
- 1-[(3-Fluorophenyl)methyl]-3-piperidinecarboxylic acid
- 896046-85-8
- 1-(3-fluorobenzyl)piperidine-3-carboxylic acid
- AKOS022179848
- DTXSID40405252
- 1-(3-Fluorobenzyl)piperidine-3-carboxylic acid
- 1-[(3-fluorophenyl)methyl]-3-Piperidinecarboxylic acid
- 1-[(3-fluorophenyl)methyl]piperidine-3-carboxylic acid
MDL Number
MFCD05170990
FAQ
What are the physical and chemical properties of 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-85-8)?
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid is a white to light yellow crystalline solid with a molecular weight of approximately 284.23 g/mol. It is slightly soluble in water but soluble in common organic solvents such as ethanol and acetone. The compound has a moderate reactivity, particularly with nucleophiles, and is stable under normal storage conditions but hydrolyzes slowly in basic media.
How is 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-85-8) typically synthesized?
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid is typically synthesized through a multistep reaction starting with 3-fluorobenzyl chloride and piperidine. The key steps involve the formation of an acyl chloride followed by condensation with piperidine, with careful control of reaction conditions to ensure high yield and selectivity. Commonly used catalysts include phosphorous oxychloride or thionyl chloride.
What industries use 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-85-8)?
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid is primarily used in the pharmaceutical industry for the synthesis of drug candidates, particularly in the development of analgesics and anti-inflammatory agents. It is also explored in the polymer industry for its potential use in the formulation of biomedical polymers and in the electronics sector for its suitability in semiconductor applications.
What precautions should be taken when handling 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-85-8)?
When handling 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be immediately neutralized with an appropriate base and cleaned up with absorbent material. Always consult the safety data sheet (SDS) for detailed information on handling and disposal.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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