Methyl 8-methylquinoline-7-carboxylate

Basic Information

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CAS Number

1030846-94-6

Molecular Formula

C12H11NO2

Molecular Weight

201.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

323.1±22.0°C at 760 mmHg

SMILES

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CC1=C(C=CC2=C1N=CC=C2)C(=O)OC

InChI

InChI=1S/C12H11NO2/c1-8-10(12(14)15-2)6-5-9-4-3-7-13-11(8)9/h3-7H,1-2H3

InChIKey

HYUFGCAJWJEANP-UHFFFAOYSA-N

LogP

2.32982

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

242

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Methyl 8-methylquinoline-7-carboxylate
7-Quinolinecarboxylic acid, 8-Methyl-, Methyl ester
AK117598
HYUFGCAJWJEANP-UHFFFAOYSA-N
0743AA
AX8219506
7-Quinolinecarboxylicacid,8-methyl-,methylester
C71130
MFCD23099491
DS-5036
Methyl8-methylquinoline-7-carboxylate
DA-16129
SB71519
SCHEMBL3502575
CS-W004242
DTXSID20731667
7-Quinolinecarboxylic acid, 8-methyl-, methyl ester
A896625
AKOS016000271
1030846-94-6

MDL Number

MFCD23099491

FAQ

What are the physical and chemical properties of Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6)?

Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) is a crystalline solid with a molecular weight of approximately 208.24 g/mol. It has limited water solubility and is slightly soluble in common organic solvents like acetone and ethyl acetate. Chemically, it is stable under normal conditions but can undergo acid-catalyzed hydrolysis. It is used in organic synthesis and has potential applications in医药和材料科学领域。

How is Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) typically synthesized?

Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) is typically synthesized through the condensation of 8-methylquinoline-7-carboxylic acid with methyl alcohol, followed by esterification. This reaction is usually catalyzed by a strong acid such as sulfuric acid and proceeds under reflux conditions for a few hours. The product is isolated by recrystallization from an appropriate solvent, yielding a pure crystalline form with good yield and selectivity.

What industries use Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6)?

Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6) is primarily used in the pharmaceutical and material science industries. It serves as a precursor in the synthesis of various organic compounds and is also utilized in the development of advanced materials. Its unique chemical structure makes it suitable for applications in the preparation of sensors and semiconductors.

What precautions should be taken when handling Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6)?

When handling Methyl 8-methylquinoline-7-carboxylate (CAS: 1030846-94-6), it is important to follow standard safety procedures. Wear appropriate personal protective equipment, including gloves, safety goggles, and protective clothing. Work in a well-ventilated area or fume hood to avoid inhalation of vapors. Store it in a dry, cool place, away from heat and sources of ignition. In case of spill, neutralize with an appropriate agent and dispose of according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS).