Compound Q&A
How is 1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-85-8) typically synthesized?
Answer
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid is typically synthesized through a multistep reaction starting with 3-fluorobenzyl chloride and piperidine. The key steps involve the formation of an acyl chloride followed by condensation with piperidine, with careful control of reaction conditions to ensure high yield and selectivity. Commonly used catalysts include phosphorous oxychloride or thionyl chloride.
About
CAS No
896046-85-8
English Name
1-(3-Fluorobenzyl)-3-piperidinecarboxylic acid
Molecular Formula
C13H16FNO2
Molecular Weight
237.27 g/mol
SMILES
C1CC(CN(C1)CC2=CC(=CC=C2)F)C(=O)O
InChIKey
VWUDHUJSDJLKJL-UHFFFAOYSA-N
Last Updated: 2026-03-04 16:30
