3-Bromo-5-nitropyridin-4-amine

Basic Information

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CAS Number

89284-05-9

Molecular Formula

C5H4BrN3O2

Molecular Weight

218.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

174-175 ºC

Boiling Point

346.5℃ at 760 mmHg

Density

1.929

Flash Point

163.4℃

Refractive Index

1.682

SMILES

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C1=C(C(=C(C=N1)Br)N)[N+](=O)[O-]

InChI

InChI=1S/C5H4BrN3O2/c6-3-1-8-2-4(5(3)7)9(10)11/h1-2H,(H2,7,8)

InChIKey

UXDLBXRMNSJEPB-UHFFFAOYSA-N

LogP

2.43890

Complexity

160

Synonyms & References

English

4-AMINO-3-BROMO-5-NITROPYRIDINE
3-Bromo-5-nitropyridin-4-amine
4-Pyridinamine,3-bromo-5-nitro-
PubChem6651
KSC496E9N
3-bromo-5-nitro-4-pyridinamine
UXDLBXRMNSJEPB-UHFFFAOYSA-N
EBD28229
BCP04745
3-bromanyl-5-nitro-pyridin-4-amine
TRA0055947
CM10992
PB14257
3-BROMO-5-NITRO-4-PYRIDYLAMINE
SY007040
BC003172
AB0027392
3-BRO
3-Bromo-5-nitro-4-pyridinamine (ACI)
Pyridine, 4-amino-3-bromo-5-nitro- (6CI, 7CI)
3-bromo-5-nitro-pyridin-4-amine
4-Amino-3-bromo-5-nitropyridine, AldrichCPR
MFCD01646057
AC-25210
4-Amino-3-bromo-5-nitropyridine
SCHEMBL1958391
Z1238547212
J-512049
BDBM626215
CS-W006864
DB-004460

MDL Number

MFCD01646057

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Bromo-5-nitropyridin-4-amine (CAS: 89284-05-9)?

3-Bromo-5-nitropyridin-4-amine is a solid at room temperature, with a crystalline form. Its molecular weight is approximately 243.02 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and dimethylformamide. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is 3-Bromo-5-nitropyridin-4-amine (CAS: 89284-05-9) typically synthesized?

3-Bromo-5-nitropyridin-4-amine is synthesized through a multi-step process, often involving the bromination of 5-nitropyridin-4-amine followed by amination of 5-bromopyridin-4-amine. Commonly, this involves using bromine and a Lewis acid catalyst like aluminum bromide. The reaction yields a product with excellent selectivity, and the overall yield is typically around 70-80%.

What industries use 3-Bromo-5-nitropyridin-4-amine (CAS: 89284-05-9)?

3-Bromo-5-nitropyridin-4-amine is used in various industries, particularly in the pharmaceutical industry for synthesizing complex organic compounds and drug candidates. It is also utilized in the production of certain chemical sensors and materials for semiconductors. Its application in polymer chemistry is less common but still relevant.

What precautions should be taken when handling 3-Bromo-5-nitropyridin-4-amine (CAS: 89284-05-9)?

When handling 3-Bromo-5-nitropyridin-4-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to avoid inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbent materials. Consult the Safety Data Sheet (SDS) for detailed information and emergency procedures.