methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate | CAS No. 885326-87-4
methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate
Basic Information
CAS Number
885326-87-4
Molecular Formula
C12H15BrN2O4
Molecular Weight
331.17 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- DTXSID30648595
- METHYL 4-BROMO-6-[(TERT-BUTOXYCARBONYL)AMINO]PYRIDINE-2-CARBOXYLATE
- AKOS015901532
- 4-Bromo-6-[(Tert-Butoxycarbonyl)Amino]Pyridine-2-CarboxylicAcidMethylEster
- AKTYIVKMAJBROD-UHFFFAOYSA-N
- methyl 4-bromo-6-t-butoxycarbonylamino-pyridine-2-carboxylate
- AMY36589
- Methyl 4-bromo-6-((tert-butoxycarbonyl)-amino)picolinate
- 4-bromo-6-(boc-amino)pyridine-2-carboxylic acid methyl ester
- Methyl4-bromo-6-((tert-butoxycarbonyl)amino)picolinate
- 4-Bromo-6-[(tert-butoxycarbonyl)amino]pyridine-2-carboxylic acid methyl ester
- SCHEMBL397093
- methyl 4-bromo-6-(tert-butoxycarbonyl)picolinate
- methyl 4-bromo-6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-2-carboxylate
- methyl 4-bromo-6-tert-butoxycarbonylaminopyridine-2-carboxylate
- C12H15BrN2O4
- Methyl 4-bromo-6-((tert-butoxycarbonyl)amino)picolinate
- FT-0743733
- 885326-87-4
- 4-BROMO-6-[(TERT-BUTOXYCARBONYL)AMINO]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- Methyl 4-bromo-6-((tert-butoxycarbonyl)amino)picolite
MDL Number
MFCD11226180
Customs Code
2933399090
FAQ
What are the physical and chemical properties of methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4)?
Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is a crystalline compound with a molecular weight of approximately 386.11 g/mol. It has a low solubility in water but good solubility in organic solvents like methanol and acetone. This compound is generally stable under normal conditions but can be reactive towards strong bases. It is an important intermediate in organic synthesis, particularly in medicinal chemistry.
How is methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) typically synthesized?
Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is synthesized by reacting methyl 4-bromo-6-aminopyridine-2-carboxylate with tert-butyl chloroformate in the presence of a base like triethylamine. The reaction is typically carried out in a suitable organic solvent such as dichloromethane. The product shows high yield and selectivity under these conditions.
What industries use methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4)?
Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the development of new materials, such as polymers and sensors, due to its functional groups.
What precautions should be taken when handling methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4)?
When handling methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using suitable absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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