methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate(CAS: 885326-87-4)

Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is a crystalline compound with a molecular weight of approximately 386.11 g/mol. It has a low solubility in water but good solubility in organic solvents like methanol and acetone. This compound is generally stable under normal conditions but can be reactive towards strong bases. It is an important intermediate in organic synthesis, particularly in medicinal chemistry.

Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is synthesized by reacting methyl 4-bromo-6-aminopyridine-2-carboxylate with tert-butyl chloroformate in the presence of a base like triethylamine. The reaction is typically carried out in a suitable organic solvent such as dichloromethane. The product shows high yield and selectivity under these conditions.

Methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the development of new materials, such as polymers and sensors, due to its functional groups.

When handling methyl 4-bromo-6-(tert-butoxycarbonylamino)pyridine-2-carboxylate (CAS: 885326-87-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using suitable absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.