tert-Butyl (3-amino-4-chlorophenyl)carbamate

Basic Information

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CAS Number

885270-73-5

Molecular Formula

C11H15ClN2O2

Molecular Weight

242.71 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC(C)(C)OC(=O)NC1=CC(=C(C=C1)Cl)N

InChI

InChI=1S/C11H15ClN2O2/c1-11(2,3)16-10(15)14-7-4-5-8(12)9(13)6-7/h4-6H,13H2,1-3H3,(H,14,15)

InChIKey

DBQDDWSYKOTBGD-UHFFFAOYSA-N

LogP

3.2692000000000005

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

253

Synonyms & References

English

Carbamic acid,N-(3-amino-4-chlorophenyl)-, 1,1-dimethylethyl ester
(3-Amino-4-chloro-phenyl)-carbamic acid tert-butyl ester
(3-AMINO-4-CHLOROPHENYL)CARBAMIC ACID TERT-BUTYL ESTER,
tert-Butyl (3-amino-4-chlorophenyl)carbamate
tert-butyl N-(3-amino-4-chlorophenyl)carbamate
(3-amino-4-chlorophenyl)-carbamic acid tert-butyl ester
1,1-dimethylethyl (3-amino-4-chlorophenyl)carbamate
2-Amino-4-Boc-amino-phenylchloride
TERT-BUTYL 3-AMINO-4-CHLOROPHENYLCARBAMATE
1,1-Dimethylethyl N-(3-amino-4-chlorophenyl)carbamate (ACI)
Carbamic acid, (3-amino-4-chlorophenyl)-, 1,1-dimethylethyl ester (9CI)
1,1-Dimethylethyl (3-amino-4-chlorophenyl)carbamate
885270-73-5
(3-Amino-4-chloro-phenyl)-carbamic acid tert-butyl ester, AldrichCPR
AKOS022364436
(3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
DTXSID00697656
MFCD04114552
SCHEMBL4013659
EN300-315133
AS-30165
tert-Butyl(3-amino-4-chlorophenyl)carbamate
DBQDDWSYKOTBGD-UHFFFAOYSA-N
AB18558
CS-0083456
DB-077355

MDL Number

MFCD04114552

Customs Code

2924299090

FAQ

What are the physical and chemical properties of tert-Butyl (3-amino-4-chlorophenyl)carbamate (CAS: 885270-73-5)?

tert-Butyl (3-amino-4-chlorophenyl)carbamate is a white crystalline solid with a molecular weight of approximately 268.03 g/mol. It has limited water solubility but is more soluble in organic solvents like methanol and ethanol. The compound is known for its low reactivity under normal conditions but shows some tendency to hydrolyze in basic media. It exhibits good stability under neutral and acidic conditions.

How is tert-Butyl (3-amino-4-chlorophenyl)carbamate (CAS: 885270-73-5) typically synthesized?

tert-Butyl (3-amino-4-chlorophenyl)carbamate is usually synthesized by the reaction of 3-chloro-4-(tert-butoxycarbonylamino)phenyl isocyanate with an amine. Common catalysts include triethylamine, and the reaction typically proceeds in organic solvents like dichloromethane. Yields are generally high, and the method provides good control over product purity.

What industries use tert-Butyl (3-amino-4-chlorophenyl)carbamate (CAS: 885270-73-5)?

tert-Butyl (3-amino-4-chlorophenyl)carbamate is primarily used in the pharmaceutical industry for the production of certain medications. It is also relevant in the polymer industry for modifying materials and in the sensor sector for developing chemical sensors due to its functional groups.

What precautions should be taken when handling tert-Butyl (3-amino-4-chlorophenyl)carbamate (CAS: 885270-73-5)?

When handling tert-Butyl (3-amino-4-chlorophenyl)carbamate, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed guidelines on storage and disposal.