Compound Q&A

How is tert-Butyl (3-amino-4-chlorophenyl)carbamate (CAS: 885270-73-5) typically synthesized?

Answer

tert-Butyl (3-amino-4-chlorophenyl)carbamate
tert-Butyl (3-amino-4-chlorophenyl)carbamate is usually synthesized by the reaction of 3-chloro-4-(tert-butoxycarbonylamino)phenyl isocyanate with an amine. Common catalysts include triethylamine, and the reaction typically proceeds in organic solvents like dichloromethane. Yields are generally high, and the method provides good control over product purity.

About

English Name tert-Butyl (3-amino-4-chlorophenyl)carbamate
Molecular Formula C11H15ClN2O2
Molecular Weight 242.71 g/mol
SMILES CC(C)(C)OC(=O)NC1=CC(=C(C=C1)Cl)N
InChIKey DBQDDWSYKOTBGD-UHFFFAOYSA-N
Last Updated: 2025-12-31 06:49

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