1-(2-Pyridinyl)-3-piperidinecarboxylic acid

Basic Information

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CAS Number

876718-04-6

Molecular Formula

C11H14N2O2

Molecular Weight

206.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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O=C(C1CN(C2=NC=CC=C2)CCC1)O

InChI

InChI=1S/C11H14N2O2/c14-11(15)9-4-3-7-13(8-9)10-5-1-2-6-12-10/h1-2,5-6,9H,3-4,7-8H2,(H,14,15)

InChIKey

QZQCXIGVFAOJNE-UHFFFAOYSA-N

LogP

1.3826

Topological Polar Surface Area

53.43000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-(Pyridin-2-yl)piperidine-3-carboxylic acid
TIMTEC-BB SBB011141
1-(2-Pyridinyl)-3-piperidinecarboxylic acid
1-pyridin-2-ylpiperidine-3-carboxylic acid
3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRIDINYL-3-CARBOXYLIC ACID,
3-4-5-6-Tetrahydro-2H--1-2-bipyridinyl-3-carboxylic-acid
1-pyridin-2-ylpiperidine-3-carboxylic acid(SALTDATA: FREE)
3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-3-carboxylic acid
1-(2-Pyridinyl)-3-piperidinecarboxylic acid (ACI)
3,4,5,6-Tetrahydro-2H-[1,2′]bipyridinyl-3-carboxylic acid

MDL Number

MFCD06738899

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-(2-Pyridinyl)-3-piperidinecarboxylic acid (CAS: 876718-04-6)?

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is a solid crystalline compound with a molecular weight of approximately 220.22 g/mol. It has low solubility in water but is more soluble in organic solvents like methanol and ethanol. The compound is moderately reactive towards bases and can form salts. It decomposes above 300°C.

How is 1-(2-Pyridinyl)-3-piperidinecarboxylic acid (CAS: 876718-04-6) typically synthesized?

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is synthesized by the condensation of 2-pyridinecarboxaldehyde with 3-piperidinone. Commonly, the reaction is catalyzed by an acid, and the product can be isolated by recrystallization from an appropriate solvent. The yield is typically around 85% with good selectivity.

What industries use 1-(2-Pyridinyl)-3-piperidinecarboxylic acid (CAS: 876718-04-6)?

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is used in the pharmaceutical industry as a precursor for drug synthesis, particularly in the development of anti-inflammatory and antiviral drugs. It is also utilized in polymer science for the modification of polymers and in the production of sensors and semiconductors.

What precautions should be taken when handling 1-(2-Pyridinyl)-3-piperidinecarboxylic acid (CAS: 876718-04-6)?

When handling 1-(2-Pyridinyl)-3-piperidinecarboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures. Proper storage should be in a cool, dry place away from direct sunlight and heat sources.