1-(2-Pyridinyl)-3-piperidinecarboxylic acid(CAS: 876718-04-6)

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is a solid crystalline compound with a molecular weight of approximately 220.22 g/mol. It has low solubility in water but is more soluble in organic solvents like methanol and ethanol. The compound is moderately reactive towards bases and can form salts. It decomposes above 300°C.

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is synthesized by the condensation of 2-pyridinecarboxaldehyde with 3-piperidinone. Commonly, the reaction is catalyzed by an acid, and the product can be isolated by recrystallization from an appropriate solvent. The yield is typically around 85% with good selectivity.

1-(2-Pyridinyl)-3-piperidinecarboxylic acid is used in the pharmaceutical industry as a precursor for drug synthesis, particularly in the development of anti-inflammatory and antiviral drugs. It is also utilized in polymer science for the modification of polymers and in the production of sensors and semiconductors.

When handling 1-(2-Pyridinyl)-3-piperidinecarboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures. Proper storage should be in a cool, dry place away from direct sunlight and heat sources.