[4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol | CAS No. 875548-97-3
[4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol
Basic Information
CAS Number
875548-97-3
Molecular Formula
C18H18F4O2
Molecular Weight
342.33 g/mol
AD
Basic Physical Properties
Density
1.221±0.06 g/cm3 (20 ºC 760 Torr)
Synonyms & References
English
- 4'-FLUORO-2'-METHOXY-5'-ISOPROPYL-4-TRIFLUOROMETHYL-1,1'-BIPHENYL-2-METHANOL
- (4'-Fluoro-5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-yl)methanol
- [2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methanol
- [4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl)biphenyl-2-yl]methanol
- {2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5-(trifluoromethyl)phenyl}methanol
- (4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanol
- [4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methanol
- (4'-fluoro-5'
- 4′-Fluoro-2′-methoxy-5′-(1-methylethyl)-4-(trifluoromethyl)[1,1′-biphenyl]-2-methanol (ACI)
- (4′-Fluoro-5′-isopropyl-2′-methoxy-4-trifluoromethyl-biphenyl-2-yl)methanol
- [2-(4-Fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methanol
MDL Number
MFCD16294184
FAQ
What are the physical and chemical properties of [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3)?
The compound [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3) is a crystalline solid with a molecular weight of approximately 544.95 g/mol. It has low water solubility but good solubility in organic solvents like methanol. This compound shows reactive electrophilic substitution properties and is less reactive towards nucleophilic attacks.
How is [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3) typically synthesized?
This compound is typically synthesized via a multi-step process involving Friedel-Crafts alkylation, followed by a series of protective group manipulations and deprotection steps. The synthesis involves the use of strong Lewis acids and organic solvents. The final step involves methanolysis to obtain the desired methanol derivative with excellent yield and selectivity.
What industries use [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3)?
This compound is primarily used in the pharmaceutical industry for the synthesis of complex drug molecules due to its unique electronic properties. It also finds applications in the polymer industry for developing advanced materials with specific functional groups. Additionally, it is used in the sensor and semiconductor industries for its electronic and optical properties.
What precautions should be taken when handling [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3)?
When handling [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3), it is important to wear protective equipment such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be handled according to the Material Safety Data Sheet (MSDS) guidelines. Always refer to the current version of the SDS for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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