Compound Q&A
How is [4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol (CAS: 875548-97-3) typically synthesized?
Answer
![[4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol](https://static.chemtradehub.com/structs/875/875548-97-3-cf00.webp "[4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol")
This compound is typically synthesized via a multi-step process involving Friedel-Crafts alkylation, followed by a series of protective group manipulations and deprotection steps. The synthesis involves the use of strong Lewis acids and organic solvents. The final step involves methanolysis to obtain the desired methanol derivative with excellent yield and selectivity.
About
CAS No
875548-97-3
English Name
[4'-Fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-2-biphenylyl]methanol
Molecular Formula
C18H18F4O2
Molecular Weight
342.33 g/mol
SMILES
OCc1cc(ccc1c1cc(C(C)C)c(cc1OC)F)C(F)(F)F
InChIKey
XSZIJSCGSTXKKI-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
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