Dimethyl (3-fluoro-2-nitrophenyl)malonate | CAS No. 872141-24-7
Dimethyl (3-fluoro-2-nitrophenyl)malonate
Basic Information
CAS Number
872141-24-7
Molecular Formula
C11H10FNO6
Molecular Weight
271.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- MFCD20441782
- BS-24207
- W12082
- OGJCUSFTJIEQRF-UHFFFAOYSA-N
- dimethyl (3-fluoro-2-nitrophenyl)malonate
- dimethyl 2-(3-fluoro-2-nitrophenyl)propanedioate
- 872141-24-7
- CS-0039111
- Dimethyl2-(3-fluoro-2-nitrophenyl)malonate
- DTXSID50647601
- SCHEMBL3655785
- A862723
- 2-(3-Fluoro-2-nitro-phenyl)-malonic acid dimethyl ester
- Dimethyl (3-fluoro-2-nitrophenyl)propanedioate
- dimethyl 2-(3-fluoro-2-nitro-phenyl)-malonate
- Dimethyl 2-(3-fluoro-2-nitrophenyl)malonate
- AKOS015907880
- Dimethyl 2-(3-fluoro-2-nitrophenyl)malote
MDL Number
MFCD20441782
Customs Code
2917399090
FAQ
What are the physical and chemical properties of Dimethyl (3-fluoro-2-nitrophenyl)malonate (CAS: 872141-24-7)?
Dimethyl (3-fluoro-2-nitrophenyl)malonate is a crystalline solid with a molecular weight of approximately 297.05 g/mol. It is slightly soluble in water but has good solubility in organic solvents like ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles and reducing agents. Its physical properties include a melting point of 75-77°C and a density around 1.32 g/cm³.
How is Dimethyl (3-fluoro-2-nitrophenyl)malonate (CAS: 872141-24-7) typically synthesized?
Dimethyl (3-fluoro-2-nitrophenyl)malonate is typically synthesized via the esterification of 3-fluoro-2-nitrophenyl malonic acid with dimethyl carbonate in the presence of a catalyst like triethylamine. The reaction is performed under mild conditions, leading to a yield of about 85-90%. The process is selective and environmentally friendly, making it a preferred method for industrial synthesis.
What industries use Dimethyl (3-fluoro-2-nitrophenyl)malonate (CAS: 872141-24-7)?
Dimethyl (3-fluoro-2-nitrophenyl)malonate finds applications in the pharmaceutical industry for drug synthesis, particularly in the development of antibacterial and antiviral compounds. It is also utilized in the production of polymers for specialty applications and as a precursor in the development of advanced sensors and semiconductors.
What precautions should be taken when handling Dimethyl (3-fluoro-2-nitrophenyl)malonate (CAS: 87214-24-7)?
When handling Dimethyl (3-fluoro-2-nitrophenyl)malonate, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to prevent inhalation. In case of spills, immediately clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions. Always store the compound in a cool, dry place away from heat and ignition sources.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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