Compound Q&A
How is Dimethyl (3-fluoro-2-nitrophenyl)malonate (CAS: 872141-24-7) typically synthesized?
Answer
Dimethyl (3-fluoro-2-nitrophenyl)malonate is typically synthesized via the esterification of 3-fluoro-2-nitrophenyl malonic acid with dimethyl carbonate in the presence of a catalyst like triethylamine. The reaction is performed under mild conditions, leading to a yield of about 85-90%. The process is selective and environmentally friendly, making it a preferred method for industrial synthesis.
About
CAS No
872141-24-7
English Name
Dimethyl (3-fluoro-2-nitrophenyl)malonate
Molecular Formula
C11H10FNO6
Molecular Weight
271.2 g/mol
SMILES
COC(=O)C(C1=C(C(=CC=C1)F)[N+](=O)[O-])C(=O)OC
InChIKey
OGJCUSFTJIEQRF-UHFFFAOYSA-N
Last Updated: 2026-03-05 06:57
