4-Cyclopropoxyphenylboronic acid

Basic Information

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CAS Number

871829-90-2

Molecular Formula

C9H11BO3

Molecular Weight

178 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

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B(C1=CC=C(C=C1)OC2CC2)(O)O

InChI

InChI=1S/C9H11BO3/c11-10(12)7-1-3-8(4-2-7)13-9-5-6-9/h1-4,9,11-12H,5-6H2

InChIKey

IZOOGQYKHWNGOK-UHFFFAOYSA-N

LogP

-0.09240000000000026

Topological Polar Surface Area

49.69 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

162

Synonyms & References

English

(4-Cyclopropoxyphenyl)boronic acid
Boronic acid, [4-(cyclopropyloxy)phenyl]-
(4-cyclopropyloxyphenyl)boronic acid
4-CYCLOPROPOXYPHENYLBORONIC ACID
C9H11BO3
IZOOGQYKHWNGOK-UHFFFAOYSA-N
4-cyclopropoxybenzene boronic acid
[4-(Cyclopropyloxy)phenyl]boronic acid
MB06315
SY025522
ST24020557
V8403
(4-cyclopropoxyphenyl)boronic acid
F11406
CS-0030605
4-cyclopropyloxyphenylboronic acid
MFCD08461663
SCHEMBL3005784
4-CYCLOPROPOXYPHENYLBORONICACID
871829-90-2
AKOS006289004
EN300-263151
WJB82990
DB-367713
Z1198179892
DTXSID70681860
(4-cyclopropyloxyphenyl)boronic Acid
AS-47013

MDL Number

MFCD08461663

FAQ

What are the physical and chemical properties of 4-Cyclopropoxyphenylboronic acid (CAS: 871829-90-2)?

4-Cyclopropoxyphenylboronic acid is a white or off-white crystalline solid with a molecular weight of approximately 262.3 g/mol. It has good solubility in organic solvents like dichloromethane and poor solubility in water. The compound exhibits electrophilic reactivity towards nucleophiles and can undergo various reactions such as coupling reactions. It is stable under normal conditions but should be stored away from moisture and strong acids.

How is 4-Cyclopropoxyphenylboronic acid (CAS: 871829-90-2) typically synthesized?

4-Cyclopropoxyphenylboronic acid can be synthesized via the boronation of 4-hydroxybenzaldehyde with cyclopropanol in the presence of a boronic acid catalyst, such as tetrakis(triphenylphosphine)palladium(0), in the presence of a base like triethylamine. The reaction typically yields a product with a high degree of purity and selectivity, with a yield of around 70-80%.

What industries use 4-Cyclopropoxyphenylboronic acid (CAS: 871829-90-2)?

4-Cyclopropoxyphenylboronic acid is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a precursor for the production of various polymers and in the sensor industry for the fabrication of chemical and biological sensors. Additionally, it is used in the semiconductor industry for the production of specific materials.

What precautions should be taken when handling 4-Cyclopropoxyphenylboronic acid (CAS: 871829-90-2)?

When handling 4-Cyclopropoxyphenylboronic acid (CAS: 871829-90-2), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.