(3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one | CAS No. 85281-85-2

(3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one

Basic Information

CAS Number

85281-85-2

Molecular Formula

C10H14O5

Molecular Weight

214.22 g/mol

AD

Basic Physical Properties

Melting Point

102-105 °C

Boiling Point

438.6°C at 760 mmHg

Density

1.39

Flash Point

179.6°C

Refractive Index

1.552

C1CCC2(CC1)O[C@H]3[C@@H](O2)C(=O)OC3O

InChI

InChI=1S/C10H14O5/c11-8-6-7(9(12)13-8)15-10(14-6)4-2-1-3-5-10/h6-8,11H,1-5H2/t6-,7+,8?/m0/s1

InChIKey

GHGRKHAVPBZSIH-KJFJCRTCSA-N

LogP

0.3059999999999999

Topological Polar Surface Area

64.99000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

284

Synonyms & References

English

  • Soy flour
  • (+)-2,3-Cyclohexylidene-L-erythruronic acid
  • 2,3-O-CYCLOHEXYLIDENE-L(-)-ERYTHRURONOLACTONE
  • (+)-2,3-CYCLOHEXYLIDENE-L-ERTHURONIC ACID
  • (+)-L-2,3-Cyclohexylideneerythruronic acid
  • 2,3-O-CYCLOHEXYLIDENE-L-(-)-ERYTHRURONIC
  • L-(-)-2,3-CYCLOHEXYLIDENE-ERTHURONIC ACID
  • L-(-)-2,3-CYCLOHEXYLIDENE-L-ERYTHRURONIC ACID
  • Spirocyclohexane-1,2-furo3,4-d1,3dioxol-4(3aH)-one,dihydro-6-hydroxy-,(3aR,6R,6aS)

FAQ

What are the physical and chemical properties of (3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one (CAS: 85281-85-2)?

The compound (3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one has a crystalline form with a molecular weight of approximately 302.27 g/mol. It has a low solubility in water but is soluble in organic solvents like dichloromethane and ethanol. Chemically, it is reactive towards nucleophiles and can undergo various ring-opening reactions. It is also known to be sensitive to air and moisture, requiring storage under inert conditions.

How is (3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one (CAS: 85281-85-2) typically synthesized?

The compound is typically synthesized through a multi-step process that involves the condensation of a furan derivative with a cyclohexanol followed by a ring closure reaction. Specific conditions such as the use of a Lewis acid catalyst and the application of heat are crucial for high selectivity and yield. The process requires precise control of reaction conditions to avoid side products and ensure high purity.

What industries use (3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one (CAS: 85281-85-2)?

This compound is used in the pharmaceutical industry for the development of certain drugs due to its unique structural features. It is also utilized in the polymer industry to enhance the properties of certain materials. Additionally, it has applications in the production of sensors and semiconductors where its chemical structure allows for specific interactions and functionalities.

What precautions should be taken when handling (3a'R,6a'S)-6'-Hydroxydihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one (CAS: 85281-85-2)?

When handling this compound, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handling should be conducted in a well-ventilated area or under a fume hood due to its reactivity. Spills should be handled by professional personnel using appropriate cleanup procedures and equipment. Safety data sheets (SDS) should be consulted for detailed safety information and emergency procedures.

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