2-Chloro-3-(trifluoromethyl)benzoyl chloride

Basic Information

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CAS Number

850156-39-7

Molecular Formula

C8H3Cl2F3O

Molecular Weight

243.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

224

Density

1.506±0.06 g/cm3 (20 ºC 760 Torr)

Flash Point

101.4±27.3℃

SMILES

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ClC(=O)c1cccc(c1Cl)C(F)(F)F

InChI

InChI=1S/C8H3Cl2F3O/c9-6-4(7(10)14)2-1-3-5(6)8(11,12)13/h1-3H

InChIKey

PKEMXTIVOBWBNO-UHFFFAOYSA-N

LogP

3.737800000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Safety Information

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Hazard Statement

Synonyms & References

English

2-CHLORO-3-(TRIFLUOROMETHYL)BENZOYL CHLORIDE
2-Chloro-3-(trifluoromethyl)benzoyl chloride 98%
2-Chloro-3-(trifluoromethyl)benzoylchloride98%
2-Chloro-3-(chlorocarbonyl)benzotrifluoride
Benzoyl chloride,2-chloro-3-(trifluoromethyl)-
SKL1211
2-Chloro-3-(trifluoromethyl)benzoyl chloride
2-chloro-3-trifluoromethylbenzoyl chloride
C8H3Cl2F3O
2-chloro-3-trifluoromethylbenzoic acid chloride
JRD-1285
ZLD0242

MDL Number

MFCD04115830

Customs Code

2916399090

FAQ

What are the physical and chemical properties of 2-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS: 850156-39-7)?

2-Chloro-3-(trifluoromethyl)benzoyl chloride is a white crystalline solid with a molecular weight of approximately 255.04 g/mol. It is slightly soluble in water but highly soluble in organic solvents such as dichloromethane and ethanol. This compound is highly reactive and susceptible to hydrolysis, making it useful in various synthetic reactions.

How is 2-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS: 850156-39-7) typically synthesized?

2-Chloro-3-(trifluoromethyl)benzoyl chloride is typically synthesized by reacting trifluoromethylbenzoic acid chloride with chlorine in the presence of a phase transfer catalyst. The reaction is exothermic and requires careful monitoring to prevent side reactions, ensuring a yield of up to 90%.

What industries use 2-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS: 850156-39-7)?

2-Chloro-3-(trifluoromethyl)benzoyl chloride is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds, as well as in the polymer industry for the production of specialty polymers. It also has applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS: 850156-39-7)?

When handling 2-Chloro-3-(trifluoromethyl)benzoyl chloride, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up promptly using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures.