Lewis B tetrasaccharide

Basic Information

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CAS Number

80081-06-7

Molecular Formula

C26H45NO19

Molecular Weight

675.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1C(C(C(C(O1)OC2C(OC(C(C2OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)C)O)O)O)NC(=O)C)O)CO)O)O)O

InChI

InChI=1S/C26H45NO19/c1-6-12(31)15(34)18(37)24(40-6)44-20-10(5-29)42-23(39)11(27-8(3)30)21(20)45-26-22(17(36)14(33)9(4-28)43-26)46-25-19(38)16(35)13(32)7(2)41-25/h6-7,9-26,28-29,31-39H,4-5H2,1-3H3,(H,27,30)

InChIKey

OXNGKCPRVRBHPO-UHFFFAOYSA-N

LogP

-7.549799999999998

Topological Polar Surface Area

316.23999999999995 Å²

Hydrogen Bond Donor/Acceptor

12 / 20

Complexity

997

Synonyms & References

English

alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc
Fucalpha1-2Galbeta1-3(Fucalpha1-4)GlcNAcbeta
80081-06-7
Fucalpha1-4[Fucalpha1-2Galbeta1-3]GlcNAcbeta-
alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-beta-D-GlcpNAc
Le(b)
Lewis b
alpha-L-fucopyranosyl-(1->4)-[alpha-L-fucopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->3)]-2-acetamido-2-deoxy-beta-D-glucopyranose
Lewis-b tetrasaccharide
Epitope ID:137354
6-deoxy-alpha-L-galactopyranosyl-(1->4)-[6-deoxy-alpha-L-galactopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->3)]-2-acetamido-2-deoxy-beta-D-glucopyranose
N-((2R,3R,4R,5S,6R)-4-(((2R,3R,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxy-6-(hydroxymethyl)-5-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide
Q27126712
DTXSID80587905
Lewis b Tetrasaccharide
Fuca1-2Galb1-3(Fuca1-4)GlcNAcb
CHEBI:59441
alpha-L-fucosyl-(1->4)-[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)]-N-acetyl-beta-D-glucosamine
alpha-L-fucosyl-(1->4)-[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)]-2-acetamido-2-deoxy-beta-D-glucose
LEWIS B TETRASACCHARIDE
Lewisb (Leb) tetraose - 5 mg
2)-b-D-galactopyranosyl-(1&reg
3)]-2-(acetylamino)-2-deoxy-
Lewis B tetrasaccharide

MDL Number

MFCD01632618

FAQ

What are the physical and chemical properties of Lewis B tetrasaccharide (CAS: 80081-06-7)?

Lewis B tetrasaccharide is a white crystalline solid with a molecular weight of approximately 612.3 g/mol. It has a high solubility in water and is moderately reactive under mild conditions. The compound exhibits good stability under normal storage conditions but requires protection from moisture and light.

How is Lewis B tetrasaccharide (CAS: 80081-06-7) typically synthesized?

Lewis B tetrasaccharide is typically synthesized through a series of glycosylation reactions using activated sugars and a Mitsunobu reaction as a key step. The synthesis involves the use of triphenylphosphine and diisopropyl azodicarboxylate as the reducing reagent, yielding a product with high selectivity and good yield.

What industries use Lewis B tetrasaccharide (CAS: 80081-06-7)?

Lewis B tetrasaccharide is primarily used in the pharmaceutical industry for the development of antimicrobial agents and in the production of certain drugs. It also finds applications in the polymer industry for the synthesis of biodegradable polymers and in the biotechnology sector for affinity chromatography and diagnostics.

What precautions should be taken when handling Lewis B tetrasaccharide (CAS: 80081-06-7)?

When handling Lewis B tetrasaccharide, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.