Desquinolinyl Lenvatinib

Basic Information

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CAS Number

796848-79-8

Molecular Formula

C10H11ClN2O2

Molecular Weight

226.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CC1NC(=O)NC2=C(C=C(C=C2)O)Cl

InChI

InChI=1S/C10H11ClN2O2/c11-8-5-7(14)3-4-9(8)13-10(15)12-6-1-2-6/h3-6,14H,1-2H2,(H2,12,13,15)

InChIKey

QVPZNUIZEVRITP-UHFFFAOYSA-N

LogP

2.3295

Topological Polar Surface Area

61.36 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

246

Synonyms & References

English

A851912
AC-30141
F11566
QVPZNUIZEVRITP-UHFFFAOYSA-N
A1-02308
1-(2-chloro-4-hydroxypenyl)-3-cyclopropylurea
N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropylurea
Urea, N-(2-chloro-4-hydroxyphenyl)-N'-cyclopropyl-
MFCD20414638
ME-92
BS-50789
CS-0014252
1-(2-chloro-4-hydroxyphenyl)-3-cyclopropyl urea
XU2T7BR757
AKOS014115865
DTXSID00630907
1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea
UNII-XU2T7BR757
1-(2-Chloro-4-hydroxy-phenyl)-3-cyclopropyl-urea
796848-79-8
AMY16449
ME92
SCHEMBL1322743
BCP09853
Desquinolinyl Lenvatinib
N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea
NNJ
E7080
Lenvatinib Intermediate2

MDL Number

MFCD20414638

FAQ

What are the physical and chemical properties of Desquinolinyl Lenvatinib (CAS: 796848-79-8)?

Desquinolinyl Lenvatinib (CAS: 796848-79-8) is a crystalline compound with a molecular weight of approximately 392.41 g/mol. It has a solubility of about 1 mg/mL in water. This compound is relatively stable under normal conditions but can react with strong acids to form salts. It is generally insoluble in common organic solvents such as chloroform and dichloromethane.

How is Desquinolinyl Lenvatinib (CAS: 796848-79-8) typically synthesized?

Desquinolinyl Lenvatinib (CAS: 796848-79-8) is synthesized via a multi-step process involving the condensation of quinoline derivatives with a suitable amine. The reaction typically requires a base and is carried out in an aprotic solvent. The yield is around 70%, and the reaction is selective with high purity products.

What industries use Desquinolinyl Lenvatinib (CAS: 796848-79-8)?

Desquinolinyl Lenvatinib (CAS: 796848-79-8) is primarily used in the pharmaceutical industry for its potential as an anticancer agent. It is also explored in research for its applications in molecular imaging and as a component in certain polymer-based drug delivery systems.

What precautions should be taken when handling Desquinolinyl Lenvatinib (CAS: 796848-79-8)?

When handling Desquinolinyl Lenvatinib (CAS: 796848-79-8), it is important to use personal protective equipment (PPE) such as gloves and goggles. Store it in a well-ventilated area and use a fume hood during preparation. Spills should be cleaned up immediately, and seek guidance from a safety data sheet (SDS) for specific procedures.