Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate | CAS No. 79607-22-0

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate

Basic Information

CAS Number

79607-22-0

Molecular Formula

C12H10ClNO3

Molecular Weight

251.67 g/mol

AD

Basic Physical Properties

Density

1.351

CCOC(=O)C1=CNC2=C(C1=O)C=C(C=C2)Cl

InChI

InChI=1S/C12H10ClNO3/c1-2-17-12(16)9-6-14-10-4-3-7(13)5-8(10)11(9)15/h3-6H,2H2,1H3,(H,14,15)

InChIKey

ABZXBXREXPKTCN-UHFFFAOYSA-N

LogP

2.3582

Topological Polar Surface Area

59.16 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

367

Synonyms & References

English

  • Oprea1_851756
  • A866636
  • ethyl 6-chloro-4-hydroxy-3-quinoline-carboxylate
  • ethyl 6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
  • 5J-026
  • HMS550J19
  • 79607-22-0
  • SR-01000530466
  • ethyl 6-chloro-4-hydroxyquinoline-3-carboxylate
  • ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate
  • DTXSID30990485
  • MFCD01847816
  • BB 0222257
  • ethyl 6-chloro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
  • AMY27059
  • Ethyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
  • FT-0641282
  • 6-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
  • J-650143
  • 6-chloro-4-hydroxyquinoline-3-carboxylic acid, ethyl ester
  • SB71246
  • MFCD00173342
  • SR-01000425944
  • SC4415
  • 6-Chloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester
  • ABZXBXREXPKTCN-UHFFFAOYSA-N
  • 6-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester
  • Oprea1_373223
  • AKOS000605906
  • AB04303
  • 70271-77-1

MDL Number

MFCD01847816

FAQ

What are the physical and chemical properties of Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate (CAS: 79607-22-0)?

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate is a crystalline compound with a molecular weight of approximately 266.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and ethyl acetate. Chemically, it is relatively stable but can react with bases to form the corresponding quinoline carboxylate salts. It exhibits moderate reactivity in nucleophilic substitution reactions.

How is Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate (CAS: 79607-22-0) typically synthesized?

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate can be synthesized using a multi-step process involving the reaction of 6-chloro-4-hydroxy-3-quinolinecarboxylic acid with ethyl bromide in the presence of a base like sodium hydride. The reaction yields a high purity product with good selectivity and yield, making it a common method for laboratory synthesis.

What industries use Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate (CAS: 79607-22-0)?

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate is primarily used in the pharmaceutical industry due to its pharmacological properties. It is also utilized in the development of sensors and as a building block for organic semiconductors. Its unique chemical structure makes it valuable in polymer synthesis and other specialized applications.

What precautions should be taken when handling Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate (CAS: 79607-22-0)?

When handling Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the use of a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately with appropriate absorbents, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.

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