Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate(CAS: 79607-22-0)

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate is a crystalline compound with a molecular weight of approximately 266.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and ethyl acetate. Chemically, it is relatively stable but can react with bases to form the corresponding quinoline carboxylate salts. It exhibits moderate reactivity in nucleophilic substitution reactions.

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate can be synthesized using a multi-step process involving the reaction of 6-chloro-4-hydroxy-3-quinolinecarboxylic acid with ethyl bromide in the presence of a base like sodium hydride. The reaction yields a high purity product with good selectivity and yield, making it a common method for laboratory synthesis.

Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate is primarily used in the pharmaceutical industry due to its pharmacological properties. It is also utilized in the development of sensors and as a building block for organic semiconductors. Its unique chemical structure makes it valuable in polymer synthesis and other specialized applications.

When handling Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the use of a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately with appropriate absorbents, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.