2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate | CAS No. 781649-86-3

2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate

Basic Information

CAS Number

781649-86-3

Molecular Formula

C15H24N4O2

Molecular Weight

292.38 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)N1CCC(CC1)NC2=C(N=CC=C2)N

InChI

InChI=1S/C15H24N4O2/c1-15(2,3)21-14(20)19-9-6-11(7-10-19)18-12-5-4-8-17-13(12)16/h4-5,8,11,18H,6-7,9-10H2,1-3H3,(H2,16,17)

InChIKey

NRYFFLQIEZSPBO-UHFFFAOYSA-N

LogP

2.475200000000001

Topological Polar Surface Area

80.48 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

348

Synonyms & References

English

  • MFCD13184780
  • FT-0687627
  • CS-M0488
  • tert-butyl 4[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate
  • A9856
  • BG-0046
  • 1-Piperidinecarboxylic acid, 4-[(2-aMino-3-pyridinyl)aMino]-, 1,1-diMethylethyl ester
  • tert-butyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate
  • 2-Amino-3-[(1-tert-butoxycarbonylpiperidin-4-yl)amino)pyridine
  • 2-amino-3-[(1-tert-butoxycarbonylpiperidin-4-yl)amino]pyridine
  • AKOS015917816
  • 2-Amino-3-[[1-(tert-butoxycarbonyl)piperidin-4-yl]amino]pyridine
  • NRYFFLQIEZSPBO-UHFFFAOYSA-N
  • 2-Amino-3-[(1-t-butoxycarbonylpiperidin-4-yl)amino)pyridine
  • 2-amino-3-[(1-t-butoxycarbonylpiperidin-4-yl)amino]pyridine
  • 781649-86-3
  • tert-Butyl 4-((2-aminopyridin-3-yl)amino)piperidine-1-carboxylate
  • SCHEMBL1198309
  • ISOPROPYL2-(4-CHLOROPHENOXY)-2-METHYLPROPANOATE
  • tert-Butyl 4-[(2-aminopyridin-3-yl)-amino]piperidine-1-carboxylate
  • tert-Butyl4-((2-aminopyridin-3-yl)amino)piperidine-1-carboxylate
  • 743JAQ2WE9
  • DTXSID00624482
  • tert-butyl 4-(2-aminopyridin-3-ylamino)piperidine-1-carboxylate
  • 1-Piperidinecarboxylic acid, 4-[(2-amino-3-pyridinyl)amino]-, 1,1-dimethylethyl ester
  • 1-Piperidinecarboxylic acid, 4-[(2-amino-3-pyridinyl)amino]-, 1,1-dimethylethyl ester
  • TERT-BUTYL 4-[(2-AMINOPYRIDIN-3-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
  • 2-amino-3-((1-tert-butoxycarbonylpiperidin-4-yl)amino)pyridine
  • AK127927
  • I14-9274
  • KB-80903

MDL Number

MFCD13184780

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate (CAS: 781649-86-3)?

2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate is a crystalline compound with a molecular weight of approximately 339.36 g/mol. It has a high solubility in organic solvents like methanol and ethyl acetate. The compound exhibits moderate reactivity, especially towards nucleophiles and is typically stable under normal storage conditions. Due to its functional groups, it can participate in various chemical reactions, including esterification and condensation reactions.

How is 2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate (CAS: 781649-86-3) typically synthesized?

2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate is commonly synthesized using a multi-step process involving the condensation of a pyridine derivative with a piperidine carboxylic acid ester. The synthesis typically employs catalytic amounts of a Lewis acid such as aluminum chloride. The method ensures high yield and good selectivity, making it a suitable route for commercial production.

What industries use 2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate (CAS: 781649-86-3)?

2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate is primarily used in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of various medicinals. It is also of interest in the polymer industry for its potential to improve material properties, and in the sensor and semiconductor industries due to its functional groups.

What precautions should be taken when handling 2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate (CAS: 781649-86-3)?

When handling 2-Methyl-2-propanyl 4-[(2-amino-3-pyridinyl)amino]-1-piperidinecarboxylate, it is important to use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a dry, well-ventilated area away from direct sunlight. In case of a spill, it should be handled using appropriate cleanup methods, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed handling instructions and emergency procedures.

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