3-Fluoro-4-nitropyridine 1-oxide

Basic Information

View in Editor

CAS Number

769-54-0

Molecular Formula

C5H3FN2O3

Molecular Weight

158.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

122 ºC

Density

1.56

SMILES

View in Editor

C1=C[N+](=CC(=C1[N+](=O)[O-])F)[O-]

InChI

InChI=1S/C5H3FN2O3/c6-4-3-7(9)2-1-5(4)8(10)11/h1-3H

InChIKey

QHWIGULJOZAPAQ-UHFFFAOYSA-N

LogP

1.68560

Complexity

160

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-fluoro-4-nitro-1-pyridin-1-one
3-fluoro-4-nitro-1-oxidopyridin-1-ium
3-Fluoro-4-nitro-1-oxido-pyridin-1-ium
Pyridine, 3-fluoro-4-nitro-, 1-oxide
AC-23130
A838916
FT-0600217
3-fluoro-1-hydroxy-4-nitro-pyridin-1-ium
QHWIGULJOZAPAQ-UHFFFAOYSA-N
AM87192
3-fluoro-4-nitropyridine1-oxide
DTXSID00344032
J-512505
Pyridine,3-fluoro-4-nitro-,1-oxide
769-54-0
MFCD00234027
3-Fluoro-4-nitropyridine 1-oxide
SCHEMBL1815079
CL0135
SY027868
PB24629
AKOS006273061
3-Fluoro-4-nitropyridine N-oxide
3-fluoro-4-nitropyridin-1-ium-1-olate
3-fluoro-4-nitro-pyridine-N-oxide
4-nitro-3-fluoropyridine N-oxide
AS-14950
EN300-210124
3-Fluoro-4-nitropyridine-N-oxide
3-fluoro-4-nitropyridine-1-oxide
3-Fluor-4-nitro- pyridin-N-oxid

MDL Number

MFCD00234027

FAQ

What are the physical and chemical properties of 3-Fluoro-4-nitropyridine 1-oxide (CAS: 769-54-0)?

3-Fluoro-4-nitropyridine 1-oxide is a crystalline solid with a molecular weight of approximately 222.04 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is highly reactive towards reducing agents and can undergo substitution reactions. It is commonly used in the synthesis of various pyridine derivatives.

How is 3-Fluoro-4-nitropyridine 1-oxide (CAS: 769-54-0) typically synthesized?

3-Fluoro-4-nitropyridine 1-oxide can be synthesized by the nitration of 3-fluoropyridine followed by oxidation of the nitro group to the 1-oxide form. This process typically involves the use of nitric acid and sulfuric acid as reagents. The reaction is selective and yields a high percentage of the desired product.

What industries use 3-Fluoro-4-nitropyridine 1-oxide (CAS: 769-54-0)?

3-Fluoro-4-nitropyridine 1-oxide is primarily used in the pharmaceutical and chemical industries for the synthesis of various intermediates and active pharmaceutical ingredients (APIs). It is also used in the production of sensors and in research for semiconductor applications.

What precautions should be taken when handling 3-Fluoro-4-nitropyridine 1-oxide (CAS: 769-54-0)?

When handling 3-Fluoro-4-nitropyridine 1-oxide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be performed in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed safety information.