3-Fluoro-4-nitropyridine 1-oxide(CAS: 769-54-0)

3-Fluoro-4-nitropyridine 1-oxide is a crystalline solid with a molecular weight of approximately 222.04 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is highly reactive towards reducing agents and can undergo substitution reactions. It is commonly used in the synthesis of various pyridine derivatives.

3-Fluoro-4-nitropyridine 1-oxide can be synthesized by the nitration of 3-fluoropyridine followed by oxidation of the nitro group to the 1-oxide form. This process typically involves the use of nitric acid and sulfuric acid as reagents. The reaction is selective and yields a high percentage of the desired product.

3-Fluoro-4-nitropyridine 1-oxide is primarily used in the pharmaceutical and chemical industries for the synthesis of various intermediates and active pharmaceutical ingredients (APIs). It is also used in the production of sensors and in research for semiconductor applications.

When handling 3-Fluoro-4-nitropyridine 1-oxide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be performed in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed safety information.