1-(2,6-Dichloro-3-fluorophenyl)ethanol

Basic Information

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CAS Number

756520-66-8

Molecular Formula

C8H7Cl2FO

Molecular Weight

207.03 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

261.3°C at 760 mmHg

Density

1.406±0.06 g/cm3 (20 ºC 760 Torr)

Flash Point

111.848℃

SMILES

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CC(C1=C(C=CC(=C1Cl)F)Cl)O

InChI

InChI=1S/C8H7Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-4,12H,1H3

InChIKey

JAOYKRSASYNDGH-UHFFFAOYSA-N

LogP

3.2191799999999997

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

156

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

CS-0005816
EN300-30544
1-(2,6-dichloro-3-fluoro-phenyl)ethanol
1-(2 pound not6-Dichloro-3-fluorophenyl)ethanol
BCP21310
MFCD09863793
SCHEMBL488680
AKOS000126451
SY009739
MFCD09863794
SY009738
(+/-)1-(2,6-dichloro-3-fluorophenyl)ethanol
Z228586386
1-(2,6-dichloro-3-fluorophenyl)ethanol
756520-66-8
1-(2,6-Dichloro-3-fluoro-phenyl)-ethanol
AC-33544
C8H7Cl2FO
DS-11516
AM20060789
NS00007893
FT-0696761
SB39291
FT-0682386
SY005058
MFCD08443334
1-(2.6-dichloro-3-fluorophenyl)ethanol
BCP06524
1-(2,6-Dichloro-3-fluoro-phenyl)-ethanol, AldrichCPR
1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
CS-W019578

MDL Number

MFCD08443334

Customs Code

2906299090

FAQ

What are the physical and chemical properties of 1-(2,6-Dichloro-3-fluorophenyl)ethanol (CAS: 756520-66-8)?

1-(2,6-Dichloro-3-fluorophenyl)ethanol is a white crystalline solid with a molecular weight of approximately 277.04 g/mol. It has a high solubility in organic solvents such as ethanol and acetone but is only slightly soluble in water. The compound exhibits typical chemical reactivity of an alcohol, including nucleophilic substitution and esterification reactions. It is also known for its stability under normal conditions but can degrade upon exposure to strong bases or light.

How is 1-(2,6-Dichloro-3-fluorophenyl)ethanol (CAS: 756520-66-8) typically synthesized?

1-(2,6-Dichloro-3-fluorophenyl)ethanol is commonly synthesized by the reaction of 2,6-dichloro-3-fluorophenol with ethyl chloroformate in the presence of a base such as sodium hydride. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The product can be isolated by recrystallization from an appropriate solvent.

What industries use 1-(2,6-Dichloro-3-fluorophenyl)ethanol (CAS: 756520-66-8)?

1-(2,6-Dichloro-3-fluorophenyl)ethanol is used in the pharmaceutical industry for the synthesis of various intermediates and final products. It is also employed in the polymer industry for the development of functional polymers. Additionally, it has applications in the semiconductor industry for the fabrication of organic thin-film transistors and sensors due to its molecular structure and chemical reactivity.

What precautions should be taken when handling 1-(2,6-Dichloro-3-fluorophenyl)ethanol (CAS: 756520-66-8)?

When handling 1-(2,6-Dichloro-3-fluorophenyl)ethanol, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using the appropriate absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and storage information.