Compound Q&A

How is 1-(2,6-Dichloro-3-fluorophenyl)ethanol (CAS: 756520-66-8) typically synthesized?

Answer

1-(2,6-Dichloro-3-fluorophenyl)ethanol
1-(2,6-Dichloro-3-fluorophenyl)ethanol is commonly synthesized by the reaction of 2,6-dichloro-3-fluorophenol with ethyl chloroformate in the presence of a base such as sodium hydride. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The product can be isolated by recrystallization from an appropriate solvent.

About

English Name 1-(2,6-Dichloro-3-fluorophenyl)ethanol
Molecular Formula C8H7Cl2FO
Molecular Weight 207.03 g/mol
SMILES CC(C1=C(C=CC(=C1Cl)F)Cl)O
InChIKey JAOYKRSASYNDGH-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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