1,4-Diisopropoxybenzene

Basic Information

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CAS Number

7495-78-5

Molecular Formula

C12H18O2

Molecular Weight

194.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

264.8 °C at 760 mmHg

Density

0.951

Flash Point

93 °C

Refractive Index

1.48

SMILES

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CC(C)OC1=CC=C(C=C1)OC(C)C

InChI

InChI=1S/C12H18O2/c1-9(2)13-11-5-7-12(8-6-11)14-10(3)4/h5-10H,1-4H3

InChIKey

HXINKONAVYDDKZ-UHFFFAOYSA-N

LogP

3.261000000000002

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

128

Synonyms & References

English

7495-78-5
UNII-4N5KZZ57YO
FT-0657686
4N5KZZ57YO
HXINKONAVYDDKZ-UHFFFAOYSA-N
P-DIISOPROPOXYBENZENE
1,4-Diisopropoxybenzene
SCHEMBL125543
AS-14368
NSC 407768
CS-0358044
NSC-407768
DTXSID3064726
Benzene, 1,4-bis(1-methylethoxy)-
A838281
1,4-di(propan-2-yloxy)benzene
hydroquinone di-isopropyl ether
Benzene,4-bis(1-methylethoxy)-
MFCD00128849
BENZENE, P-DIISOPROPOXY-
1,4-BIS(1-METHYLETHOXY)BENZENE
p-Diisopropoxy Benzene
NSC407768
AKOS006241635
1,4-di-iso-propoxybenzene
1,4-Diisopropoxy-benzol
Benzene,4-bis(1-methylethoxy)
Hydrochino-di-isopropylether
Hydrochinondi-isopropylether
p-di-isopropoxybenzene
Benzene,p-diisopropoxy- (8CI)

MDL Number

MFCD00128849

FAQ

What are the physical and chemical properties of 1,4-Diisopropoxybenzene (CAS: 7495-78-5)?

1,4-Diisopropoxybenzene (CAS: 7495-78-5) is a clear, colorless liquid with a molecular weight of approximately 230.39 g/mol. It has a low boiling point of around 155°C and a high melting point of 10-11°C. This compound is sparingly soluble in water but miscible with common organic solvents. It is relatively non-reactive under normal conditions but can undergo electrophilic substitution reactions under strong conditions.

How is 1,4-Diisopropoxybenzene (CAS: 7495-78-5) typically synthesized?

1,4-Diisopropoxybenzene (CAS: 7495-78-5) is typically synthesized via the Friedel-Crafts alkylation of benzene using diisopropyl ether as the alkylating agent. This process can be catalyzed by aluminum chloride. The reaction is carried out under anhydrous conditions to avoid side reactions. The yield is usually around 80-90%, with good selectivity for the 1,4 position.

What industries use 1,4-Diisopropoxybenzene (CAS: 7495-78-5)?

1,4-Diisopropoxybenzene (CAS: 7495-78-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of polymers and as a precursor in the development of sensors and semiconductors. Due to its chemical structure, it plays a significant role in the fine chemical sector, particularly in the development of new materials and drugs.

What precautions should be taken when handling 1,4-Diisopropoxybenzene (CAS: 7495-78-5)?

When handling 1,4-Diisopropoxybenzene (CAS: 7495-78-5), it is advisable to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the area is well-ventilated or use a fume hood during handling to avoid inhalation of vapors. Spills should be handled with absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.