Compound Q&A

How is 1,4-Diisopropoxybenzene (CAS: 7495-78-5) typically synthesized?

Answer

1,4-Diisopropoxybenzene
1,4-Diisopropoxybenzene (CAS: 7495-78-5) is typically synthesized via the Friedel-Crafts alkylation of benzene using diisopropyl ether as the alkylating agent. This process can be catalyzed by aluminum chloride. The reaction is carried out under anhydrous conditions to avoid side reactions. The yield is usually around 80-90%, with good selectivity for the 1,4 position.

About

CAS No 7495-78-5
English Name 1,4-Diisopropoxybenzene
Molecular Formula C12H18O2
Molecular Weight 194.27 g/mol
SMILES CC(C)OC1=CC=C(C=C1)OC(C)C
InChIKey HXINKONAVYDDKZ-UHFFFAOYSA-N
Last Updated: 2026-01-07 14:58

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