(2R)-Amino(3,5-dinitrophenyl)acetic acid

Basic Information

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CAS Number

74927-72-3

Molecular Formula

C8H7N3O6

Molecular Weight

345.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

216-217 °C

Boiling Point

480.21°C (rough estimate)

Density

1.3660 (rough estimate)

Flash Point

298.2°C

Refractive Index

-102 ° (C=1, THF)

Specific Rotation

-99.0° - -104.0° (c=1, THF)

SMILES

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OC(=O)[C@H](NC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-])c2ccccc2

InChI

InChI=1S/C8H7N3O6/c9-7(8(12)13)4-1-5(10(14)15)3-6(2-4)11(16)17/h1-3,7H,9H2,(H,12,13)/t7-/m1/s1

InChIKey

UVOWPSUNIJUNGB-SSDOTTSWSA-N

LogP

3.49600

Complexity

514

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-(-)-N-(3,5-Dinitrobenzoyl)-alpha-phenylglycine
(2R)-2-[(3,5-dinitrobenzoyl)amino]-2-phenylacetic acid
(R)-(-)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine
N-(3,5-Dinitrobenzoyl)-D-alpha-phenylglycine
N-(3,5-Dinitrobenzoyl)phenylglycine
(R)-(-)-n-(3,5-dinitrobenzoyl)-a-phenylglycine
DNBPG
(2r)-[(3,5-dinitrobenzoyl)amino](phenyl)acetic acid
R-(-)-N-(3,5-Dinitrobenzoyl)phenylglycine
PubChem8095
MIVUDAUOXJDARR-CYBMUJFWSA-N
(r)-n-(3,5-dinitrobenzoyl)phenylglycine
ST50307183
D1853
N-(3,5-Dini
(2R)-2-[(3,5-dinitrobenzoyl)amino]-2-phenyl-acetic acid

MDL Number

MFCD00010134

Customs Code

2924299090

FAQ

What are the physical and chemical properties of (2R)-Amino(3,5-dinitrophenyl)acetic acid (CAS: 74927-72-3)?

(2R)-Amino(3,5-dinitrophenyl)acetic acid is a crystalline solid with a molecular weight of approximately 281.04 g/mol. It has a low solubility in water but is soluble in common organic solvents. The compound is moderately reactive, particularly under acidic conditions, and can undergo nucleophilic substitution reactions.

How is (2R)-Amino(3,5-dinitrophenyl)acetic acid (CAS: 74927-72-3) typically synthesized?

(2R)-Amino(3,5-dinitrophenyl)acetic acid can be synthesized via the coupling of 3,5-dinitrobenzoic acid and glycine. The reaction typically involves the use of a condensing reagent such as dicyclohexylcarbodiimide (DCC) and 4-(dimethylamino)pyridine (DMAP) as a catalyst. The yield is usually around 70-80%, and the product is isolated by recrystallization.

What industries use (2R)-Amino(3,5-dinitrophenyl)acetic acid (CAS: 74927-72-3)?

(2R)-Amino(3,5-dinitrophenyl)acetic acid is primarily used in the pharmaceutical industry for the synthesis of various organic compounds and intermediates. It can also be applied in the polymer industry for the development of functional polymers, and in the sensor industry for the production of chemical sensors due to its unique reactivity.

What precautions should be taken when handling (2R)-Amino(3,5-dinitrophenyl)acetic acid (CAS: 74927-72-3)?

When handling (2R)-Amino(3,5-dinitrophenyl)acetic acid, proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be stored in a cool, dry place away from sources of heat and ignition. Spills should be cleaned up using appropriate absorbent materials, and the area should be ventilated. Safety data sheets (SDS) should always be consulted for detailed safety information.