4-(4-Morpholinyl)benzoic acid

Basic Information

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CAS Number

7470-38-4

Molecular Formula

C11H13NO3

Molecular Weight

207.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

277°C

Water Solubility

Slightly soluble in water.

Flash Point

203.7℃

SMILES

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C1COCCN1C2=CC=C(C=C2)C(=O)O

InChI

InChI=1S/C11H13NO3/c13-11(14)9-1-3-10(4-2-9)12-5-7-15-8-6-12/h1-4H,5-8H2,(H,13,14)

InChIKey

XVAJKPNTGSKZSQ-UHFFFAOYSA-N

LogP

1.2214

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

218

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Moisture & Light Sensitive

Synonyms & References

English

Z276509282
SY003055
4-morpholin-4-ylbenzoic acid
HMS1673G14
AR3104
4-(4-Morpholinyl)benzoic acid, 97%
4-morpholin-4-yl benzoic acid
4-(morpholine-4-yl)-benzoic acid
4-(4-Morpholinyl)benzoic Acid (contains 0.5% N,N-Dimethylformamide at maximum)
MFCD00588379
BP-10785
NSC402784
7470-38-4
4-(4-Morpholinyl)benzoicAcid
AC-2824
AB01325432-02
4-Morpholin-4-yl-benzoic acid
NSC-402784
EN300-59416
CHEBI:183418
1Y-0800
Oprea1_138719
DTXSID60996238
CS-W002645
AM20060402
A838201
Benzoic acid, 4-(4-morpholinyl)-
SCHEMBL60648
VU0011916-3
4-(4-Morpholinyl)benzoic Acid
SDCCGMLS-0065993.P001

MDL Number

MFCD00588379

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(4-Morpholinyl)benzoic acid (CAS: 7470-38-4)?

4-(4-Morpholinyl)benzoic acid is a crystalline solid with a molecular weight of approximately 233.29 g/mol. It has a pKa of about 7.9, indicating weak acidity. The compound is slightly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. It is reactive towards bases and can undergo esterification and other acid-base reactions.

How is 4-(4-Morpholinyl)benzoic acid (CAS: 7470-38-4) typically synthesized?

4-(4-Morpholinyl)benzoic acid is typically synthesized by the condensation of 4-morpholinoaniline with benzoic anhydride in the presence of a catalyst such as pyridine. The reaction mixture is heated to ensure completion, and the final product is purified by recrystallization from an appropriate solvent to obtain the crystalline form with good yield and selectivity.

What industries use 4-(4-Morpholinyl)benzoic acid (CAS: 7470-38-4)?

4-(4-Morpholinyl)benzoic acid is used in various industries. It serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of certain pain relievers and anti-inflammatory drugs. It is also utilized in the preparation of polymers and in the development of sensors and materials for semiconductors.

What precautions should be taken when handling 4-(4-Morpholinyl)benzoic acid (CAS: 7470-38-4)?

When handling 4-(4-Morpholinyl)benzoic acid, ensure the use of personal protective equipment such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate absorbents. Refer to the safety data sheet (SDS) for detailed handling and disposal instructions.