(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid

Basic Information

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CAS Number

73150-67-1

Molecular Formula

C5H4N2O3S

Molecular Weight

172.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

>300°C

Boiling Point

395.74°C at 760 mmHg

Density

1.711

Flash Point

193.1 °C

Refractive Index

1.693

SMILES

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C1=C(N=C(S1)N)C(=O)C(=O)O

InChI

InChI=1S/C5H4N2O3S/c6-5-7-2(1-11-5)3(8)4(9)10/h1H,(H2,6,7)(H,9,10)

InChIKey

VMASTYPGLHRVNL-UHFFFAOYSA-N

LogP

-0.007400000000000073

Topological Polar Surface Area

93.28 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

196

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

FT-0692595
2-(2-Aminothiazol-4-yl)glyoxylicacid
4-Thiazoleacetic acid, 2-amino-alpha-oxo-
2-Amino-4-thiazoleglyoxylic Acid
AC-077
73150-67-1
UNII-B8S9EKV7AU
SCHEMBL11037997
(2-amino-4-thiazolyl)glyoxylic acid
2-(2-Aminothiazol-4-yl)glyoxylic acid
2-(2-azanyl-1,3-thiazol-4-yl)-2-oxidanylidene-ethanoic acid
MFCD00274532
2-(2-amino-1,3-thiazol-4-yl)-2-oxoacetic acid
DS-16213
2-(2-amino-4-thiazolyl)-2-oxoacetic acid
2-Amino-alpha-oxo-4-thiazoleacetic acid
(2-aminothiazol-4-yl)glyoxylic acid
2-(2-Aminothiazol-4-yl)-2-oxoaceticacid
VMASTYPGLHRVNL-UHFFFAOYSA-N
DTXSID90223408
AKOS006271937
2-(2-amino-4-thiazolyl)glyoxylic acid
SCHEMBL2897055
B8S9EKV7AU
A837733
2-amino-thiazol-4-glyoxylic acid
EINECS 277-301-0
CS-0099900
NS00037477
2-(2-Aminothiazol-4-yl)-2-oxoacetic acid
O10456

MDL Number

MFCD00274532

Customs Code

2934100090

FAQ

What are the physical and chemical properties of (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid (CAS: 73150-67-1)?

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid has a crystalline form and a molecular weight of approximately 172.2 g/mol. It is slightly soluble in water and has a pKa of about 3.5. The compound is moderately reactive, especially in alkaline conditions. It can form complexes with metal ions and is often used in synthesis due to its functional groups.

How is (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid (CAS: 73150-67-1) typically synthesized?

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid can be synthesized through the condensation of 2-aminothiazole-4-carboxylic acid and a suitable aldehyde or ketone. Common methods include the use of a dehydrating agent like hydroxylamine or an acid catalyst. The yield is generally moderate, and the product can be purified by recrystallization or column chromatography.

What industries use (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid (CAS: 73150-67-1)?

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry for the modification of polymer properties. Additionally, it is used in the development of sensors and as a component in certain chemical reagents.

What precautions should be taken when handling (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid (CAS: 73150-67-1)?

When handling (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from heat and ignition sources. Work in a well-ventilated area or fume hood to prevent inhalation of dust or vapor. If a spill occurs, carefully clean up using absorbent materials and dispose of the waste according to local regulations. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information.