(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid(CAS: 73150-67-1)

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid has a crystalline form and a molecular weight of approximately 172.2 g/mol. It is slightly soluble in water and has a pKa of about 3.5. The compound is moderately reactive, especially in alkaline conditions. It can form complexes with metal ions and is often used in synthesis due to its functional groups.

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid can be synthesized through the condensation of 2-aminothiazole-4-carboxylic acid and a suitable aldehyde or ketone. Common methods include the use of a dehydrating agent like hydroxylamine or an acid catalyst. The yield is generally moderate, and the product can be purified by recrystallization or column chromatography.

(2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry for the modification of polymer properties. Additionally, it is used in the development of sensors and as a component in certain chemical reagents.

When handling (2-Amino-1,3-thiazol-4-yl)(oxo)acetic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from heat and ignition sources. Work in a well-ventilated area or fume hood to prevent inhalation of dust or vapor. If a spill occurs, carefully clean up using absorbent materials and dispose of the waste according to local regulations. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information.