Ivermectin | CAS No. 70288-86-7

Ivermectin

Basic Information

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CAS Number

70288-86-7

Molecular Formula

C48H74O14

Molecular Weight

875.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

155～157℃

Boiling Point

No data available

Density

Flash Point

No data available

Solubility

H2O: ≤1.0% KF

Vapor Pressure

No data available

Specific Rotation

-17 °--20° (c=0.025, in methol)

SMILES

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CC[C@@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](CC=C(C)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)C=CC=C6CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2

InChI

InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/t25-,26+,28+,30+,31+,33-,34+,35+,36+,37+,38+,39+,40-,41+,42+,43-,44+,45-,47-,48-/m1/s1

InChIKey

AZSNMRSAGSSBNP-NQSNVJSVSA-N

LogP

5.601400000000008

Topological Polar Surface Area

170.06 Å²

Hydrogen Bond Donor/Acceptor

3 / 14

Complexity

1680

Safety Information

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GHS Hazard Pictograms

H300

H351

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

H351 Suspected of causing cancer
Carcinogenicity

Hazard Class

Class 6.1 Class 6.1

Toxicity

LD50 in dogs, rhesus monkeys (mg/kg): about 80, more than 24 orally. (MSDS Merck & Co. Inc., 2003)

Synonyms & References

English

ivermectin
22,23-DIHYDROAVERMECTIN B1
22,23-DIHYDROAVERMECTINE
CARDOMEC
EQVALEN
heartgard-30
IVERMECTINE
IVOMEC
hyvermectin
mk-0933
mk933
IVERMECTIN HCL
Ivermectin EP2000
IVERMECTIN EP(CRM STANDARD)
IVERMECTIN USP(CRM STANDARD)
IvermectineEp2000
IVERMECTINE(PATENT-NOSUPPLY)
22,23-Dihydro C-076B1
Ivosint
Ivermectin Solution
IVERMECTIN, EP 7.0
Ivermecti
Mectizan
Uvemec
Vermic
WAKO090-05521
vermectin
MK-933
(4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-Butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5
Ivermectin B1a
Dihydroavermectin B1a

MDL Number

MFCD00869511

Customs Code

29322090

FAQ

What is Ivermectin (CAS: 70288-86-7)?

Ivermectin (CAS: 70288-86-7) is an antiparasitic compound classified as a macrocyclic lactone. Its chemical formula is C22H39NO12, and it exhibits high solubility in ethanol. Ivermectin is known for its broad-spectrum activity against nematodes and arthropods. It is widely used in veterinary medicine and human healthcare for treating parasitic infections. The compound’s structure contributes to its efficacy as a deworming agent, making it a key component in various pharmaceutical formulations.

What are the main uses of Ivermectin (CAS: 70288-86-7)?

Ivermectin (CAS: 70288-86-7) is primarily used to treat parasitic infections in humans and animals, such as onchocerciasis, strongyloidiasis, and scabies. It is also applied in veterinary medicine for livestock and pets. In agriculture, it serves as a pesticide to control nematodes. Additionally, it has been explored for antiviral and anti-inflammatory research. Its versatility in combating parasites makes it a critical drug in public health and livestock management.

Is Ivermectin (CAS: 70288-86-7) safe?

Ivermectin (CAS: 70288-86-7) is generally safe when used as directed, but improper handling may cause toxicity. It is a prescription medication, and overdose can lead to adverse effects like dizziness or gastrointestinal issues. Protective measures, such as gloves and goggles, are recommended during handling. Safety standards ensure its efficacy and minimize risks, emphasizing adherence to medical guidelines for human and animal use.

How should Ivermectin (CAS: 70288-86-7) be stored?

Ivermectin (CAS: 70288-86-7) should be stored in a cool, dry place away from light, typically at 20-25°C. It requires a tightly sealed container to prevent moisture exposure, which can degrade its stability. Avoiding direct sunlight and maintaining controlled humidity levels are crucial for preserving potency. Proper storage ensures safety and effectiveness for both pharmaceutical and agricultural applications.